Publications by authors named "O T Hofmann"

Article Synopsis
  • The study explores using fibrillated films for catalyst immobilization to address mass transfer issues in hydrogenation reactions, specifically converting nitrobenzene to aniline.
  • Thinner fibrillated films showed better catalytic performance by reducing mass transfer limitations compared to thicker films, leading to the development of improved film designs to enhance efficiency.
  • The findings suggest fibrillated films can be a sustainable option for continuous catalysis, potentially replacing traditional powdered catalysts while researching environmentally friendly materials for production.
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  • Scientists are collecting a lot of genetic information from many people around the world to help improve medicine and health care for everyone.
  • To make the most out of this data, we need to work together and make it easier to share it safely and fairly.
  • The article talks about ways to get better at sharing this data, including using new technology and engaging with communities, and suggests 12 important steps we can all take to make this happen.
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Whole genome and whole transcriptome sequencing (WGTS) can accurately distinguish B-cell acute lymphoblastic leukemia (B-ALL) genomic subtypes. However, whether this is economically viable remains unclear. This study compared the direct costs and molecular subtype classification yield using different testing strategies for WGTS in adolescent and young adult/adult patients with B-ALL.

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Article Synopsis
  • Hereditary mutant pheochromocytomas (PC) and paragangliomas (PG) are rare tumors that tend to metastasize unpredictably, prompting a study to better understand their genomic characteristics.
  • A multi-omic analysis of 94 tumors from 79 patients revealed distinct molecular profiles based on whether the tumors originated from sympathetic or parasympathetic cells, with specific alterations linked to metastatic behavior.
  • The study also identified high mutation loads, unusual genomic features, and mechanisms of resistance to DNA alkylating chemotherapies, enhancing the comprehension of these complex neuroendocrine tumors and their treatment responses.
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The discrete and charge-separated nature of matter - electrons and nuclei - results in local electrostatic fields that are ubiquitous in nanoscale structures and relevant in catalysis, nanoelectronics and quantum nanoscience. Surface-averaging techniques provide only limited experimental access to these potentials, which are determined by the shape, material, and environment of the nanostructure. Here, we image the potential over adatoms, chains, and clusters of Ag and Au atoms assembled on Ag(111) and quantify their surface dipole moments.

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