Publications by authors named "O Sued"
In the original publication [...
View Article and Find Full Text PDFObjectives: To evaluate the performance of Xpert MTB/RIF Ultra testing in urine samples as part of a TB screening strategy in patients with advanced HIV disease (AHD).
Methods: We conducted a multicentre prospective cohort study across three HIV reference hospitals in Brazil, between January and December 2023. The study included adult hospitalized patients with AHD, defined by a CD4 count of <200 cells/μL in the last 3 months or clinical presentation suggestive of opportunistic infection, without effective antiretroviral treatment.
Experiences and perspectives on rapid-test diagnosis of tuberculosis, histoplasmosis and cryptococcosis in people with advanced HIV/AIDS disease in Porto Alegre, Brazil.
PLoS One
November 2024
The rapid diagnosis of opportunistic infections (OIs) is critical for improving the health outcomes of people living with HIV/AIDS (PLWHA). This study aimed to describe the feasibility of implementing a package for the rapid diagnosis of tuberculosis, histoplasmosis, and cryptococcosis in patients with advanced HIV/AIDS disease in Porto Alegre, Brazil. The research involved two focus groups with health professionals, four in-depth interviews with healthcare managers, and twelve interviews with PLWHA.
View Article and Find Full Text PDFArticle Synopsis
- The prevalence of pretreatment drug resistance (PDR) to certain HIV medications is high in Belize, particularly among those with previous treatment exposure, posing a challenge for effective antiretroviral therapy (ART).
- WHO recommends dolutegravir-based ART regimens for their effectiveness and low resistance risk, which is crucial for reaching UNAIDS' target of 95% viral suppression.
- Recent surveys show that while 79.6% of adults achieved viral suppression on ART, only 50% of children and adolescents did, highlighting the need for better support and adherence to treatment.