Pulmonotoxic xenobiotics and methods of their determination in ambient air of nuclear power plant equipment.

Objective: Aim: To identify appropriate methods for determining the content of radioactive and non-radioactive pulmotoxic xenobiotics in the ambient air of NPP equipment to ensure its reliability, radiation and environmental safety, as well as to reduce the risks of occupational pathologies for workers and protect people's health.

Patients And Methods: Materials and Methods: Analytical methods of analysis of modern methods of determining the content of radioactive and non-radioactive pulmonary toxic xenobiotics in the ambient air of NPP equipment.

Conclusion: Conclusions: a) during operation of NPP equipment, pulmotoxic xenobiotics enter the surrounding air, which can then enter the human respiratory system in the form of radioactive or non-radioactive substances; b) signif i cant methods of determining the content of pulmotoxic xenobiotics in the air are: gas chroma-tography; gas chromatography-mass spectrometry; liquid scintillation; photometric, ionometric, polarographic, titrometric, turbidimetric, atomic absorption, radiometric and γ-spectrometric measurements; c) radioactive pulmonotoxic xenobiotics cause radiation pathologies in the respiratory organs as a result of internal radioactive irradiation of the body; d) the effects of non-radioactive pulmotoxic xenobiotics are accompanied by irritation and inf l ammatory processes in the respiratory organs, as well as toxic swelling of the lungs; е) there is a connection between the presence of pulmotoxic xenobiotics in the air and the course of human respiratory diseases as a result of breathing such air.

MINE-BLAST TRAUMA AS A FACTOR IN THE EARLY DEVELOPMENT OF VASCULAR DISEASES OF THE BRAIN.

Objective: The aim of this study is to investigate the state of bulbar conjunctival vessels, rheological properties of blood, catecholamines (adrenaline, norepinephrine), lipid metabolism, alkaline proteins of blood serum in patients with consequences of mild combat traumatic brain injury.

Patients And Methods: Materials and methods: 76 individuals aged 28 to 41 years were examined. The duration of the injury lasted from 2 to 4 years.

Investigation of the influence of calibration practices on cytogenetic laboratory performance for dose estimation.

Purpose: In the frame of the QA program of RENEB, an inter-laboratory comparison (ILC) of calibration sources used in biological dosimetry was achieved to investigate the influence of calibration practices and protocols on the results of the dose estimation performance as a first step to harmonization and standardization of dosimetry and irradiation practices in the European biological dosimetry network.

Materials And Methods: Delivered doses by irradiation facilities used by RENEB partners were determined with EPR/alanine dosimetry system. Dosimeters were irradiated in the same conditions as blood samples.

Strong Correlation Between mRNA Expression Levels of HIF-2α, VEGFR1, VEGFR2 and MMP2 in Laryngeal Carcinoma.

The hypoxia that arises due to the rapid proliferation of tumor cells is a fundamental driving force for the canonical pathway of neovascularization. In the current study we report a very strong correlation between mRNA expression levels of HIF-2α (but not HIF-1α), VEGFR-1, VEGFR-2 and MMP2 in ex vivo samples from laryngeal carcinoma. Sixty-three samples from patients with histopathologically verified carcinoma of the larynx were examined in this study.

Macrophageal infiltration and microvessel density in laryngeal carcinoma: study of 52 cases.

Angiogenesis is one of the six originally constituted hallmarks of cancer that has been extensively studied in the last two decades. The aim of our study is to assess the microvessel and macrophageal density in laryngeal carcinoma and its clinicopathological correlations. We immunohistochemically assessed microvessel density (CD34) and macrophage count (CD68) using microarray techniques and then looked for clinicopathological correlations.