Publications by authors named "O Soerensen"

Article Synopsis
  • Cholinergic urticaria (CholU) is a common condition where symptoms like itchy hives arise from sweating, but existing treatments often fail to provide adequate control for patients.
  • In a phase IIa trial, the new oral medication izuforant was tested on adults with CholU who didn't respond well to traditional antihistamines.
  • Results showed that while izuforant did not significantly improve the primary measures of urticaria activity, it did lead to noticeable improvements in patient-reported severity assessments compared to placebo.
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Objective: We performed a randomised controlled trial (RCT) in patients undergoing ACL reconstruction (ACLR) using either quadriceps tendon graft (QT) or semitendinosus/gracilis hamstring (STG) graft. We compared subjective outcome (primary outcome) and knee stability, donor site morbidity and function (secondary outcomes).

Methods: From 2013 to 2015, we included 99 adults with isolated ACL injuries in the RCT.

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There is no agreed definition for the assessment of vertebral fractures and deformities in patients with osteoporosis. Radiographs of 66 patients randomized for therapy with etidronate or placebo were analyzed at baseline and during follow-up (60/120/150 weeks) independently using two procedures. The first method of spinal deformity index (SDIG) and vertebral deformity score (VDSG) is based on a semiquantitative visual reading of each vertebra between T4 and L4.

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Vitamin D has been proposed as a risk factor of ischaemic heart disease. In 12 patients with acute myocardial infarction the major circulating vitamin D metabolite, 25-hydroxy-cholecalciferol (25-HCC), did not show any fluctuations during the first 4 days after onset of symptoms. The serum 25-HCC level was then measured in 128 patients consecutively admitted because of chest pain, 53 of whom had myocardial infarction and 75 had angina pectoris.

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