Publications by authors named "O Sidhom"
High prevalence of antineuronal antibodies in Tunisian psychiatric inpatients.
J Neuropsychiatry Clin Neurosci
November 2015
Article Synopsis
- The study investigated the presence of antineuronal antibodies in 103 psychiatric inpatients and 41 control subjects without malignancies or neurological issues.
- Indirect immunofluorescence testing revealed 20 patients had antineuronal nuclear autoantibodies, while some had antibodies reacting with Purkinje cell cytoplasm, but none of the controls showed similar results.
- Over a 5-year follow-up, the five patients with confirmed antibodies did not develop any neurological disorders or cancers.
Background: Burnout is a syndrome which affects preferentially help professions, having a strong emotional interpersonal implication.
Aim: To assess the prevalence of burn out in a sample of Tunisian nurses, and to determine its causes and perceived repercussions.
Methods: In a first step, we assessed the work conditions, the perceived burn out and its possible consequences in 142 nurses from 12 different wards.
One hundred and three psychiatric inpatients (74 men) were assessed for a wide spectrum of autoantibodies including antinuclear, antismooth muscle, antimitochondrial, antiDNA, anti-phospholipid, anti-cardiolipin IgG and IgM, antikeratin, rheumatoid factor, antithyroperoxydase, antigliadin IgA and IgG, antitransgutaminase, and antiendomysium antibodies. Four groups of patients were considered separately, including 47 with schizophrenia, 23 with schizoaffective disorder, 16 with bipolar disorder and 17 patients with other different psychiatric diagnosis. Forty one healthy, age- and sex-matched blood donors were used as a control group.
View Article and Find Full Text PDFThe existence of association between hyperhomocysteinaemia (HHC) and schizophrenia has been suggested by several recent studies. This study aimed to determine the prevalence of HHC and its main determinants, and sought a correlation with clinical features in Tunisian patients with schizophrenia. Plasma homocysteine (Hcy), folate, and vitamin B12, as well as the C677T methylene tetrahydrofolate reductase (MTHFR) polymorphism, were studied in 33 patients with schizophrenia, all free from antipsychotic treatment, and 35 age- and smoking-habit-matched healthy subjects as controls.
View Article and Find Full Text PDFAim: to study the clinicopathological features of the different types of appendical mucocele and to compare them with those of pseudomyxoma peritonei.
Methods: 25 cases of appendical mucocele were operated in the Cap-Bon region in Tunisia during a period of 13 years from 1994 to 2006.
Results: 9 retentionnal cysts, 13 mucinous cystadenomas, one serrated adenoma, one hyperplasia of the mucosa and one cystadenocarcinoma were diagnosed.