DeepCTG® 2.0: Development and validation of a deep learning model to detect neonatal acidemia from cardiotocography during labor.

Cardiotocography (CTG) is the main tool available to detect neonatal acidemia during delivery. Presently, obstetricians and midwives primarily rely on visual interpretation, leading to a significant intra-observer variability. In this paper, we build and evaluate a convolutional neural network to detect neonatal acidemia from the CTG signals during delivery on a multicenter database with 27662 cases in five centers, including 3457 and 464 cases of moderate and severe neonatal acidemia respectively (defined by a fetal pH at birth between 7.

Effectiveness of prophylactic carbetocin versus oxytocin following vaginal delivery for preventing severe postpartum hemorrhage.

Objective: To compare the effectiveness of prophylactic carbetocin with prophylactic oxytocin for preventing severe postpartum hemorrhage (PPH) following vaginal delivery.

Methods: This before and after cohort study took place between 2020 and 2021 in a university maternity hospital. In 2021, the protocol for PPH prevention immediately after vaginal delivery changed: intravenous oxytocin (5 IU) was replaced by intravenous carbetocin (100 μg).

Effectiveness of episiotomy to prevent OASIS in nulliparous women at term.

Objective: To assess the association between episiotomy and severe obstetric anal sphincter injury (OASIS) in nulliparous women at term according to the use of an instrument for delivery with control confounding by indication.

Methods: This was an observational retrospective cohort study including 12 346 women from 2004 to 2020. All nulliparous women with a cephalic singleton pregnancy were included.

Evaluation of obstetric management of women with macrosomic foetuses in two Level 3 maternity hospitals in France and identification of predictive factors for obstetric and neonatal complications.

Objective: Foetal macrosomia is associated with high maternal and neonatal morbidity; however, obstetric management of suspected macrosomia has not been well defined. This study aimed to analyse obstetric management in a population of women who delivered macrosomic new-borns and assess maternal and neonatal outcomes and risk factors for complications in such cases.

Study Design: This two-centre retrospective study conducted in France over a 10-year period comprised 1724 women who had delivered macrosomic new-borns (defined as those whose weight was > 90th percentile according to the Association of Users of Computerised Records in Perinatology, Obstetrics, and Gynaecology curve) from 37SA.

Classification and evaluation of episiotomy practices from 2004 to 2020 and association with OASIS.

Objective: To apply a new classification based on seven clinically relevant subgroups to accurately describe episiotomy practices and evaluate the association between episiotomy and obstetrical anal sphincter injury (OASIS) rates according to the classification's subgroups.

Methods: Observational retrospective cohort study based on a population comprising 39 487 women from January 1, 2004 to December 31, 2020 in a level III university maternity unit. The primary outcome was the overall episiotomy rate in the institution and its trend over time as well as in each subgroup of obstetrical population classification.