Publications by authors named "O Schonberger"
Article Synopsis
- - A study from 2016-2020 examined the effectiveness of the Time-lapse Incubator (TLI) for improving reproductive outcomes by comparing three groups: conventional incubation, TLI with full evaluations, and TLI with limited evaluations.
- - The primary focus was on live birth rates, with no significant differences found between the groups for single or double embryo transfers, and similar pregnancy rates across all arms.
- - The findings suggested that TLI's components (undisturbed culturing and morphokinetic grading) did not provide notable extra benefits for reproductive outcomes, indicating the need for further validation through randomized controlled trials.
This multi-center study evaluated a novel microscope system capable of quantitative phase microscopy (QPM) for label-free sperm-cell selection for intracytoplasmic sperm injection (ICSI). Seventy-three patients were enrolled in four in vitro fertilization (IVF) units, where senior embryologists were asked to select 11 apparently normal and 11 overtly abnormal sperm cells, in accordance with current clinical practice, using a micromanipulator and 60× bright field microscopy. Following sperm selection and imaging via QPM, the individual sperm cell was chemically stained per World Health Organization (WHO) 2021 protocols and imaged via bright field microscopy for subsequent manual measurements by embryologists who were blinded to the QPM measurements.
View Article and Find Full Text PDFObjective: Pre-treatment (PT) therapies in IVF are known to be used as pre-stimulation modality to improve cycle outcomes. This study aims to assess whether PT in GnRH antagonist cycles triggered with GnRH-agonist impact oocyte maturation response.
Methods: Data were retrospectively collected for patients who underwent GnRH antagonist cycle with agonist triggering with and without PT.
Pregestational genetic testing of embryos is the conventional tool in detecting genetic disorders (fetal aneuploidy and monogenic disorders) for in vitro fertilization (IVF) procedures. The accepted clinical practice for genetic testing still depends on biopsy, which has the potential to harm the embryo. Noninvasive genetic prenatal testing has not yet been achieved.
View Article and Find Full Text PDFClinical outcome of planned oocyte cryopreservation at advanced age.
J Assist Reprod Genet
November 2022
Purpose: To report outcome of planned oocyte cryopreservation (POC) in the first 8 years of this treatment in our center.
Methods: A retrospective study in a university-affiliated medical center.
Results: A total of 446 women underwent POC during 2011-2018.