Publications by authors named "O Saydam"

Objective: We aimed to assess the real-world label adherence of non-vitamin K antagonist oral anticoagulant (NOAC) dosing patterns, including apixaban, edoxaban, and rivaroxaban, in Turkish patients with atrial fibrillation.

Methods: This was an observational, prospective, cross-sectional, multicenter study. Patients with atrial fibrillation (AF) who were prescribed NOACs within the last 4 months were recruited from 34 cardiology clinics in Türkiye.

View Article and Find Full Text PDF
Article Synopsis
  • * Overexpression of OTX2 in Group 3 MB cells increases growth, movement, and polarization, leading to decreased survival in animal models due to the development of brain and spinal cord metastases.
  • * OTX2 activates the mTOR gene and its signaling pathway, enhancing cell migration, with a strong correlation found between OTX2 and mTOR expression in human MB samples, suggesting potential therapeutic targets by inhibiting mTORC2.
View Article and Find Full Text PDF

Background: This study aims to investigate whether the invasive staging of aortopulmonary window lymph nodes could be omitted in the presence of a suspected isolated metastasis in the aortopulmonary window lymph node on positron emission tomography/computed tomography.

Methods: Between January 2010 and January 2016, a total of 67 patients (54 males, 13 females; mean age: 59.9±8.

View Article and Find Full Text PDF

Glioblastoma is one of the most devastating neoplasms of the central nervous system. This study focused on the development of serum extracellular vesicle (EV)-based glioblastoma tumor marker panels that can be used in a clinic to diagnose glioblastomas and to monitor tumor burden, progression, and regression in response to treatment. RNA sequencing studies were performed using RNA isolated from serum EVs from both patients ( = 85) and control donors ( = 31).

View Article and Find Full Text PDF

Background: We investigated the effect of unexpected N2 on survival in stage IIIB/N2 cases.

Methods: We retrospectively analyzed 1803 non-small cell lung cancer patients between 2010 and 2016. There were 89 patients (4.

View Article and Find Full Text PDF