Publications by authors named "O Sadr-Azodi"
Background: Helicobacter pylori (H. pylori) is an established gastric carcinogen, also associated with an increased risk of colorectal cancer. Therefore, we suspected that H.
View Article and Find Full Text PDFObjectives: We aimed to evaluate the risk of colorectal adenocarcinoma (CRA) associated with long-term use of proton pump inhibitors (PPIs) in a large nationwide cohort.
Design: Retrospective cohort study.
Setting: This research was conducted at the national level, encompassing the entire population of Sweden.
Background: Biliary tract cancer (BTC) often goes undetected until its advanced stages, resulting in a poor prognosis. Given the anatomical closeness of the gallbladder and bile ducts to the pancreas, the inflammatory processes triggered by acute pancreatitis might increase the risk of BTC.
Objective: To assess the association between acute pancreatitis and the risk of BTC.
Antipsychotic drugs and risk of acute pancreatitis: A nationwide case-control study.
Acta Psychiatr Scand
August 2023
Introduction: Use of antipsychotic drugs, especially second-generation agents, has been suggested to cause acute pancreatitis in multiple case reports; however, such an association has not been corroborated by larger studies. This study examined the association of antipsychotic drugs with risk of acute pancreatitis.
Methods: Nationwide case-control study, based on data from several Swedish registers and including all 52,006 cases of acute pancreatitis diagnosed in Sweden between 2006 and 2019 (with up to 10 controls per case; n = 518,081).
Article Synopsis
- The study investigates the outcomes of pre-emptive surgical resection for non-invasive intraductal papillary mucinous neoplasm (IPMN) compared to early-stage invasive IPMN (inv-IPMN) at Karolinska University Hospital.
- Out of 284 patients, the two-year overall survival (OS) rate was high (96%) with no significant differences between those with non-invasive IPMN and early-stage inv-IPMN (96% vs 92%).
- The findings suggest that many resections for low-grade dysplasia (LGD) do not improve survival compared to early cancer, indicating a need for more precise criteria to guide surgical decisions and minimize unnecessary surgeries.