[Relationship between biological variants of U. urealyticum and clinico-morphological manifestations of urogenital inflammation in experimental animals].

Dependence of clinicomorphological changes in urinary and sexual organs of rats on biological variants of U.urealyticum (biovar Parvo or T960) used in experimental modelling of ureaplasmic infection by two variants: a) introduction in the sterile conditions of culture U.urealyticum (10(4)-10(6) U/ml) directly into the bladder by catheterisation b) infection of female anogenital region with culture U.

[A method of genotyping clinical isolates of Ureaplasma urealyticum biovar Parvo].

A new method for typing clinical isolates of U. urealyticum (Parvo biovar) is based on SSCP analysis of amplicons of mba gene 5' region and upstream region. The mba gene is coding for MB gene of U.

[The diagnostic and therapeutic characteristics of inflammatory urogenital diseases in women associated with Ureaplasma urealyticum].

Complex examination of 40 female in- and outpatients at the age 20 to 42 years with inflammatory urogenital diseases was performed. To verify the diagnosis, current clinical, microbiological, endoscopic and ultrasonic procedure were used. It was shown that the inflammatory processes in the urogenital tracts were mainly due to association of opportunistic and/or pathogenic organisms.

[Ultrastructure of the blood-brain barrier in the cerebral cortex in atherosclerotic dementia].

Ultrastructural changes of blood-brain barrier elements were studied in the cortex of cerebral superior frontal and medial temporal gyri in atherosclerotic dementia. Destructive changes in endotheliocytes, pericytes, basement membrane and increase in number, swelling and edema of astrocyte peduncles with the inconstant approximation of astrocyte body to the capillary basement membrane were demonstrated along with signs of blood circulation decline in cortical capillaries. Lipofuscin and lipids accumulation and aggregation of homogenous material of high electron density, probably plasma proteins, were characteristic for changes in blood-brain barrier in atherosclerotic dementia, which is important in pathogenesis of this type of the disease.

[Preparation of liver cultures from human embryos].

The cultures were obtained from 9-12-week-old human embryonic liver. 24-36 hours after seeding the cultures containing a multilayer focus of adhesion and a monolayer growth zone were formed. The growth zone contained hepatocytes with bile pigment granules in the cytoplasm.