[Cerebral microangiopathy in men with obstructive sleep apnea syndrome].

Objective: To determine factors associated with the development of small vessel disease (SVD) in patients with obstructive sleep apnea syndrome (OSA).

Material And Methods: One hundred and fifty-two patients with risk factors for the development of cerebrovascular diseases were examined. Based on the results of polysomnography, patients were divided into groups with- (=84) and without (=68) OSA.

Clinical and neurophysiological characteristics of 89 patients with narcolepsy and cataplexy from the Russian Narcolepsy Network.

Study Objectives: The first reports of narcolepsy with cataplexy in Russia were made by Mankovsky (The pathogenesis of narcolepsy (the case of epidemic encephalitis with cataplexy) published in the Sovremennaya psihonevrologia) in 1925. The largest series of patients (n = 110) was reported by A. Vein (doctoral thesis: Hypersomnia Syndrome) in 1964.

[Optimization of lipid-lowering therapy in patients after ischemic stroke. Resolution of the Council of Experts].

Hyperlipidemia is the main risk factor for diseases caused by atherosclerosis including ischemic stroke. This publication provides practical recommendations and an algorithm for prescribing lipid-lowering therapy to post-ischemic stroke patients. The algorithm presents the steps for sequential administration of statins, ezetimibe, and PCSK9 inhibitors to achieve target levels of low-density lipoprotein cholesterol.

[The clinical/laboratory support for using melatonin in chronic cerebrovascular diseases and metabolic syndrome].

Aim: To evaluate a role of melatonin deficiency in the metabolic syndrome and chronic cerebral ischemia (CCI).

Material And Methods: One hundred and seventy-nine men, aged 45-75 years, with CCI and components of metabolic syndrome (MS) were examined. Intima-media thickness (IMT) in the carotid arteries and cerebrovascular reactivity was assessed by the results of duplex scanning and hypercapnic test.