Genetic Variations and Haplotypic Diversity in the Myostatin Gene of Different Cattle Breeds in Russia.

The myostatin gene () in cattle has a number of polymorphisms associated with increased muscle mass. The aim of the current study was to determine the haplotype frequencies of and polymorphisms among cattle bred for meat in Russia, using DNA analysis. Using the earlier created test systems based on the AS-PCR and PCR-RFLP methods, six populations of Aberdeen Angus ( = 684), two populations of Limousin ( = 54), one population of Simmental ( = 55), and one population of Belgian Blue ( = 137) belonging to Russian farms were genotyped on and polymorphisms.

The Molecular Bases Study of the Inherited Diseases for the Health Maintenance of the Beef Cattle.

The article highlighted the problem of meat cattle genetic defects. The aim was the development of DNA tests for some genetic defects diagnostics, the determination of the animal carriers and their frequencies tracking in time. The 1490 DNA samples from the Aberdeen Angus ( = 701), Hereford ( = 385), Simmental ( = 286) and Belgian Blue ( = 118) cattle have been genotyped on the genetic defects by newly created and earlier developed DNA tests based on AS-PCR and PCR-RFLP methods.

DNA analysis of the Russian populations of Aberdeen Angus, Hereford and Belgian Blue cattle.

The use of specialized meat breeds in cattle breeding programs is considered very promising for improving herds' productivity. However, in animal genotype, along with genes that positively affect the productivity signs, there are genes whose mutations, known as genetic defects, negatively affect the health of animals. The aim of the study was the screening of the Russian populations of Aberdeen Angus, Hereford and Belgian Blue cattle on gene mutations associated with the genetic defects of arthrogryposis multiplex (AM), osteopetrosis (OS), developmental duplication (DD), double muscling (M1), hypotrichosis (HY) and maple syrup urine disease (MSUD) as well as the polymorphism of myostatin gene () linked with the gene responsible for less fat content in the carcass by means of DNA analysis.

Screening of haplotype for cholesterol deficiency genetic defect in the Russian Holstein cattle population.

In our study, we estimated the frequency of haplotype for cholesterol deficiency (HCD) carriers in the Russian Holstein cattle population. We studied 1817 random samples of cows born in 2010-2017 from ten herds and 331 cows and heifers from the other three herds born in 2016-2019, fathers or fathers of mothers of which were HCD carriers. The method of AS-PCR was used for animals genotyping.