Publications by authors named "O S Medvedev"
Hydrogels have a wide range of medical applications, including use within implantable systems. However, when used in implants, their visibility under conventional medical imaging techniques is limited, creating safety risks for patients. In the current work, we assessed the possibility of enhancing hydrogels using Ln-based contrasting agents to facilitate their visualization in photon-counting computed tomography (PCCT).
View Article and Find Full Text PDFMolecular hydrogen (H) has antioxidant, anti-inflammatory, and anti-fibrotic effects. In a rat model simulating pulmonary fibrotic changes induced by monocrotaline-induced pulmonary hypertension (MPH), we had previously explored the impact of inhaled H on lung inflammation and blood pressure. In this study, we further focused the biological effects of H on mast cells (MCs) and the parameters of the fibrotic phenotype of the local tissue microenvironment.
View Article and Find Full Text PDFBackground: The literature on trauma-informed care practices (TIC) indicates that this framework is beneficial for young people, carers, and staff. However, a significant gap in the literature and practice is the absence of psychometrically sound scales to measure carer adherence to TIC principles. Emerging evidence suggests that TIC practices shift carer attitudes and beliefs, which mediate positive outcomes for both carers and young people.
View Article and Find Full Text PDFArticle Synopsis
- A study examined psychological factors influencing COVID-19 vaccination attitudes across four countries: Ghana, India, New Zealand, and Germany, with 1822 participants involved.
- Each country showed different key psychological predictors, such as positive affect in Ghana (7%), self-compassion in India (66%), dispositional optimism in New Zealand (5%), and compassion for others in Germany (2%).
- The findings suggest that emotional well-being is crucial for improving vaccination rates, and addressing psychological distress can also positively impact attitudes toward vaccination.
Background: The gut-liver axis and bacterial translocation are important in cirrhosis, but there is no available universal biomarker of cellular bacterial translocation, for which presepsin may be a candidate.
Aim: To evaluate the relationship of the blood presepsin levels with the state of the gut microbiota in cirrhosis in the absence of obvious infection.
Methods: This study included 48 patients with Child-Pugh cirrhosis classes B and C and 15 healthy controls.