[Clinico-experimental basis for regional and systemic administration of thiopoietins in liver cirrhosis. Report I].

The authors present results of studying the effectiveness of a new class of medicines--preparations of the group "Glutoxim" (Molixan, Redoxell, Bikvolit, Liglutin) obtained on the model of experimental cirrhosis of the liver in 76 white rats caused by dimethylnitrosamin, and describe their first experience with using thiopoietins in 24 patients with cirrhosis of the liver in a surgical clinic. It was found that three weeks of treatment with Molixan and Bikvolit gave a significant hepatoprotecting effect (less amount of the connective tissue, reduction of the dystrophic processes in hepatocytes). A positive effect of Redoxell was shown in longer time of treatment.

[Cytokines in the tear fluid and their role in the pathogenesis of ophthalmic herpes].

The papers deals with the levels of cytokines in the tear and blood serum of patients with ophthalmoherpes. Damaging the cornea, herpes virus is shown to induce the synthesis of IL-1alpha, alpha-TNF, and alpha2-INF both in the tear and serum. The levels of these cytokines are much greater than the controls.