Publications by authors named "O Rodriguez-Gomez"
Article Synopsis
- The study addresses the challenges of comparing self-perceived cognitive functioning across various aging studies by linking item-level data from international research.
- The researchers harmonized data from 24 different studies and found that certain items related to memory and executive functions provided the best measurement precision.
- This work allows for better comparison and analysis of cognitive functioning in older adults globally, potentially paving the way for improved self-report questionnaires based on the identified key items.
Article Synopsis
- The MOPEAD project aims to improve the detection and diagnosis of Alzheimer's disease (AD) through various patient-engagement strategies across five European countries.
- Four screening methods were tested: a web approach, Open-House initiatives, screenings in primary care, and by diabetes specialists, with results showing different costs per true-positive (TP) diagnosis for each method.
- Primary care and diabetes specialists were the most cost-effective methods for diagnosing AD, but their ability to identify at-risk patients effectively raises questions, suggesting a potential need for refined web and Open-House strategies.
Background: To explore whether the combination of white matter hyperintensities (WMHs) and amyloid-beta (Aβ) deposition is associated with worse cognitive performance on cognitive composites (CCs) domain scores in individuals with subjective cognitive decline (SCD).
Methods: Two hundred participants from the FACEHBI cohort underwent structural magnetic resonance imaging (MRI), F-florbetaben positron emission tomography (FBB-PET), and neuropsychological assessment. WMHs were addressed through the Fazekas scale, the Age-Related White Matter Changes (ARWMC) scale, and the FreeSurfer pipeline.
Article Synopsis
- The MOPEAD project aimed to find new ways to detect early stages of Alzheimer's disease and raise awareness about the importance of early diagnosis.
- Four different strategies were employed for early detection: a web-based prescreening tool, an open house initiative, a primary care protocol, and pre-screening in diabetes clinics.
- Out of 2,847 people screened, 1,129 were identified as high-risk for Alzheimer's, showing varying success rates among the different strategies used.
Article Synopsis
- General practitioners (GPs) are crucial for early dementia detection, but often fail to diagnose it on time, prompting a study on their attitudes and barriers in five European countries.
- Out of 343 GPs surveyed, 74% believe early diagnosis is important, but opinions vary by country regarding reimbursement and consultation time for patients.
- If an effective drug for slowing Alzheimer’s progression were available, 59% of GPs indicated they would change how they approach early diagnosis, highlighting the impact of treatment options on diagnostic practices.