Publications by authors named "O Ristow"

Article Synopsis
  • The study investigates the effectiveness of a surgical procedure (extended strip craniectomy with bilateral barrel staving) for treating isolated craniosynostosis of the sagittal suture in infants, specifically focusing on its impact on cranial shape without directly addressing forehead issues.
  • Results showed significant improvements in aspects like bossing angle and cephalic index over a year, although the cranial shape did not entirely match that of healthy peers, indicating partial normalization but not complete correction.
  • The research validates 3D photogrammetry as a useful noninvasive tool for assessing cranial changes post-surgery, suggesting potential for wider clinical applications in monitoring cranial morphology.
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Study Design: Retrospective cohort study.

Objective: A major risk factor for oral squamous cell carcinoma (OSCC) is advanced age. Ablative surgery combined with microvascular reconstruction has become routine for OSCC.

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Background: Oral squamous cell carcinoma (OSCC) ranks on position 14 in global cancer analysis and makes up to 38 % of all head and neck squamous cell carcinomas. While surgery is accepted as first-line treatment of early tumors, the reconstructive approach is not standardized. Therefore, we evaluated the concept of ablative tumor removal and microvascular reconstruction in terms of oncological safety and surgical morbidity for early OSCCs.

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Background: Lately SOX2 and SOX9, transcription factors associated with stemness-like phenotypes of cancer cells, have been linked to tumor growth, metastasis, and resistance to therapy.

Methods: This study aimed on evaluating the expression of SOX2 and SOX9 in a large cohort of patients with OSCC including primary and recurrent tumors and corresponding lymph node metastases. Semiautomatic digital pathology scoring was used to determine protein expression and survival analysis was performed to evaluate its prognostic significance.

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Objective And Aim: Challenging defect configurations and dimensions arise from severe, localized vertical alveolar ridge defects caused by trauma or prior surgery. This study aims to analyze three-dimensional bone gain, assess marginal bone stability in such defect configurations, and evaluate the impact of grafting outside the bone contour on the overall outcome, with a focus on iliac crest block grafts as a valid treatment option.

Materials And Methods: The prospective cohort study evaluated patients who required vertical block grafting due to localized bone defects in the maxilla or mandible and who had received iliac grafts.

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