Publications by authors named "O R Simon"
Background: Although the benefit of supportive care in the postcancer period is now well demonstrated, its implementation in the patient journey remains challenging. This article describes the development, since 2015 and in routine care, of supportive postcancer care comprising a multidisciplinary rehabilitation programme (MRP) based on exercise for patients with early breast cancer.
Methods: As part of quality control, we reviewed all patient files since the programme was implemented.
Patients with gastrointestinal bleeding (GIB) exhibit varying tolerances to acute blood loss. We aimed to investigate the effect of relative Hb decrease (ΔHb%) on GIB outcomes. Participants enrolled in the Hungarian GIB Registry between 2019 and 2022 were analyzed.
View Article and Find Full Text PDFThis case series describes the clinical features, diagnostic challenges, treatment approaches, and outcomes of three adult patients with COQ8A-related CoQ10 deficiency presenting with focal status epilepticus, who were effectively treated at the Department of Neurology, Philipps University Marburg, Marburg, Germany. The patients, all from consanguineous families with the first two being siblings, presented with a late onset of the disease, characterized by progressive cerebellar ataxia and epilepsy, with clinical deterioration and focal status epilepticus occurring in adulthood. The first patient exhibited myoclonic status, while the second and third patients presented with bilateral tonic-clonic seizures followed by focal status epilepticus manifesting with cortical blindness.
View Article and Find Full Text PDFLipoprotein(a) distribution in hospitalised Asian patients with ischaemic heart disease.
Ther Adv Cardiovasc Dis
December 2024
Article Synopsis
- Elevated lipoprotein(a) [Lp(a)] is linked to increased risk of ischaemic heart disease (IHD), and the study aimed to analyze IHD patients with Lp(a) measurements, focusing on the connection between elevated Lp(a) levels and premature IHD.
- A retrospective study of 521 IHD patients in Singapore revealed that 10% experienced premature IHD, with most having normal Lp(a) levels, though Indian ethnicity and female patients showed higher concentrations.
- Findings suggested that Lp(a) levels ≥155 mmol/L significantly correlate with the development of premature IHD, highlighting the influence of ethnicity and gender on Lp(a) distribution.
Article Synopsis
- The study evaluates the safety and efficacy of a new technique called soft partial release of non-aggressive stent retrievers (SPORNS) for treating very distal vessel occlusion strokes.
- There were 24 patients treated with this method, resulting in a high recanalization success rate (92%) and significant improvement in patient outcomes, as indicated by reduced NIHSS scores and a majority achieving good outcomes by day 90.
- The SPORNS technique seems to reduce the risk of bleeding complications while effectively treating small clots in distal arteries.