[Diet optimization in patients with obesity and diastolic heart failure based on the assessment of indicators of metabolism during physical exertion].

The objective of the work was to examine the performance of basal metabolism and body composition in obese patients with diastolic heart failure (DHF) to identify optimal needs of these patients in the nutrients and energy. We studied 222 patients with obesity, that were divided into four groups depending on the degree of obesity and the presence or absence of DHF with preserved systolic function of the left ventricle (2 groups of obese patients with an initial degree I-II, 2 groups - a pronounced degree of obesity III). Basal metabolism by indirect respiratory calorimetry, physical activity at home and cardiorespiratory exercise testing were evaluated in these groups of patients.

[Drug resistance of Staphylococcus aureus strains, isolated from children with intestinal dysbacteriosis].

The level of antibiotic-sensitivity of 73 S. aureus strains isolated from children with dysbacteriosis of the large intestine in an outpatient clinic was determined. The isolation rate of polyresistant strains was 44%.

[The frequency of staphylococcal colonization of the intestines in children with the manifestations of dysbacteriosis].

In 2100 children of different age groups the microbiocenosis of the large intestine was studied. The study revealed that the colonization of the mucous membrane of the large intestine with staphylococci developed in 30% of children with intestinal dysbacteriosis. Young children were mainly affected (91%).

[Effects of different types of general anesthesia on metabolic activity of erythrocytes].

The effect of general anesthesia with ether, azeotropic mixture and drugs for neuroleptanalgesia on the activity of glycolytic enzymes and the content of glycolysis metabolites in erythrocytes has been studied in 212 patients with II to IV stage gastric cancer. It has been shown that ether anesthesia and anesthesia with azeotropic mixture aggravate metabolic disturbances, while neuroleptanalgesia has no negative effect on cellular metabolism. The absence of correlation between the severity of surgical intervention and the degree of disturbances in erythrocyte metabolism indicates a sufficient anesthesiological protection when drugs for neuroleptanalgesia are used.

[Electron microscopic study of the cytopathogenic action of meningococci in a continuous human amnion cell culture].

The electron-microscopic study of the interaction of meningococci with continuous human amnion cell culture F1 has revealed that this process comprises 3 stages. The study has shown that, following the adhesion of meningococci to the surface of cells F1, these cells are invaded by individual coccal forms of meningococci. In response to infection vacuoles appear in the cytoplasm of the cells.