Publications by authors named "O Prem Das"
Background: Traumatic brain injury (TBI) is a significant cause of morbidity and mortality in the older adult population, and palliative care consultation can assist in goals-of-care discussions. However, patterns of hospital care delivered before consultation are understudied for older adult patients with TBI. The objective of this study was to identify demographic and clinical drivers of preconsultation care intensity in this population.
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- The study examines the inconsistent timing of palliative care consultations for traumatic brain injury (TBI) patients, using machine learning to identify patient characteristics and factors affecting consultation timing.
- Three patient clusters were identified: older White women received the earliest consultations, older White men had delayed consultations, and middle-aged non-White patients faced the longest delays, highlighting disparities based on demographics.
- Key factors influencing the timing of consultations include age, sex, and race, indicating a need for more equitable palliative care strategies in TBI management.
Background: The benefit of distal embolite penetration for middle meningeal artery (MMA) embolization in chronic subdural hematomas (cSDH) remains controversial.
Objective: To compare the use of diluted Onyx with undiluted Onyx in the management of cSDH.
Methods: This is a retrospective study of patients with cSDH who underwent MMA embolization using Onyx 18 at our institution.
Background: Transradial approach (TRA) has been increasingly utilized in various neuroendovascular interventions as a safe alternative to the transfemoral approach (TFA). As middle meningeal artery (MMA) embolization emerges as an effective therapy for treating chronic subdural hematomas (cSDH), some studies have explored using TRA. In this study, we compared procedural times and post-operative outcomes between those with TRA and TFA.
View Article and Find Full Text PDFFTY720 or fingolimod is a known functional antagonist of sphingosine-1-phosphate (S1P), and it is effective in treating multiple sclerosis and preventing inflammatory bowel disease (IBD). Evidence shows that its use in mice can increase the susceptibility to mucosal infections. Despite the significant contribution of S1P to barrier function, the effect of the administration of FTY720 on the mucosal barrier has never been investigated.
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