[GDF-15 and the risk of bleeding in patients with stable CAD receiving multicomponent antithrombotic therapy: the results of the prospective REGATA register].

Aim: To evaluate the prognostic value of GDF-15 in relation the development of bleeding and events in stable CAD patients, receiving combined antithrombotic therapy.

Materials And Methods: The data was obtained from the prospective registry REGATA, 343 CAD patients (249 males), median age 68 [IQR 62; 75] years) were enrolled. Patients with sinus rhythm and concomitant PAD received acetylsalicylic acid in combination with rivaroxaban 2.

Forecasting and diagnostics of critical states in platform-vibrator with shock.

A platform-vibrator with shock is a low-frequency machine used in the construction industry for compaction and molding of large concrete products. Its mathematical model is a two-degree-of-freedom two-body vibro-impact system with a soft impact. Some changes in its parameters can increase the machine performance and improve the product quality, but these same changes may lead to the emergence of critical states, such as coexisting regimes in hysteresis zone, chaotic motion, intermittency and crisis-induced intermittency, crises, and transient chaos.

Monomeric form of C-reactive protein in the assessment of the residual inflammatory cardiovascular risk in patients with subclinical carotid atherosclerosis.

Aim      To study the relationship between monomeric C-reactive protein (mCRP) and the progression of asymptomatic carotid atherosclerosis in patients with a moderate risk for cardiovascular diseases (CVD) as assessed with the SCORE model.Material and methods  The study included 80 men and women aged 53.1±5.

The monomeric C-reactive protein level is associated with the increase in carotid plaque number in patients with subclinical carotid atherosclerosis.

The high-sensitivity C-reactive protein (hsCRP) assay measures the level of the pentameric form of CRP in blood. Currently, there are no available assays measuring the level of the monomeric form of CRP (mCRP), produced at sites of local inflammation. We developed an assay measuring the mCRP level in blood plasma with functional beads for flow cytometry.

A MATHEMATICAL MODEL FOR PREDICTING THE OUTCOME OF TREATMENT OF MULTIDRUD-RESISTANT TUBERCULOSIS.

Objective: The aim: Predicting the effectiveness of treatment for MRI of the lungs by developing a mathematical model to predict treatment outcomes.

Patients And Methods: Materials and methods: 84 patients with MRI of the lungs: group 1 (n = 56) - with signs of effective TB treatment at the end of the intensive phase; group 2 (n = 28) - patients with signs of ineffective treatment. We used the multivariate discriminant analysis method using the statistical environment STATISTICA 13.