Publications by authors named "O Plakhotnaya"

Article Synopsis
  • New drug delivery systems that respond to stimuli have been created for injections, focusing on using smart polymers that change at the injection site.
  • Sterility is crucial for all injectable and eye medication forms, and choosing the right sterilization method is key, as it can alter the drug’s properties.
  • There is a lack of research on the risks of sterilizing these sensitive systems, but this review offers recommendations based on existing experimental data to help manage these risks.
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The subject matter of the investigation is to compare the metered dose nasal sprays containing the long-acting decongestant oxymetazoline from the different manufacturers according to the dispersion quality: the dose quantity in one packing, the dose mass reproducibility, imprint area on the planar imitation model. The tests were conducted: «The number of doses per package», «Mass uniformity of the dose», «Irrigated area (on the planar imitation model)». The analysis of nine oxymetazoline nasal sprays demonstrates that the optimal result is achieved while usingVicks Sinex.

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