Efficacy of shear wave elastography in predicting preeclampsia in the first trimester.

Objective: This study aimed to investigate the predictive value of shear wave elastography (SWE) for preeclampsia (PE) in first-trimester pregnancies.

Methods: Singleton pregnant women aged 18-45 years, who underwent routine first-trimester prenatal examinations (11-13 weeks+6 days) were enrolled. Pregnancies with anterior placenta and normal first-trimester screening test results were included in the study group.

Comparison of elasticity values in normal and gestational diabetic pregnancies in the third trimester.

Placental elasticity was compared by using Shear wave elastography (SWE) in patients with gestational diabetes mellitus (GDM) with and without insulin to non-diabetic controls. Three groups were created as follows: Group 1 ( = 79, GDM with insulin therapy), Group 2 ( = 90, GDM with only diet) and Group 3 ( = 150, healthy controls) All patients were above 36 gestational weeks with anterior placenta. Clinical trial number was also received (NCT04455880).

Pessary use in patients diagnosed with short cervix and cervical insufficiency.

Objective: The aim was to evaluate the effectiveness of Arabin pessary use in patients with cervical insufficiency or short cervix before the 24th week of gestation and the impact of cervical examination findings prior to pessary application on the outcome in terms of the gestational week.

Materials And Methods: In our study, among the pregnancies between the 12th and 24th gestational weeks, 60 pregnant women with a preterm delivery history and/or cervical length less than 25 mm were included. Among these 60 patients, 43 of them had a short cervix, 17 of them had cervical insufficiency.

Clinical significance of neuregulin 4 (NRG4) in gestational diabetes mellitus.

Objective: Gestational diabetes mellitus (GDM) is defined as glucose intolerance detected during pregnancy. GDM is increasing worldwide and is associated with adverse maternal and fetal outcomes. Neuregulin 4 (NGR4) is epidermal growth factor like signaling molecule.

Can we predict severity of intrahepatic cholestasis of pregnancy using inflammatory markers?

Objective: To investigate the association of inflammatory markers with severity of intrahepatic cholestasis of pregnancy (ICP).

Materials And Methods: This retrospective case-control study was conducted with 229 pregnant women, 84 with ICP, and 145 age-matched healthy pregnant women. Patients were categorized as mild ICP (<40 µmol/L) and severe ICP (≥40 µmol/L) with regard to serum bile acids.