Publications by authors named "O Pascu"
Spectrum of BRCA1/2 Mutations in Romanian Breast and Ovarian Cancer Patients.
Int J Environ Res Public Health
April 2022
Article Synopsis
- Approximately 10,000 women are diagnosed with breast cancer and 2,000 with ovarian cancer each year in Romania, but there are few genetic studies focused on identifying high-risk patients in the population.
- Researchers evaluated 490 women (250 with breast cancer and 240 with ovarian cancer) using Next-Generation Sequencing to examine for harmful mutations in the BRCA1 and BRCA2 genes.
- The study found a significant number of patients with BRCA mutations: 47% of breast cancer patients and 25% of ovarian cancer patients, identifying specific mutation variants that could help in genetic testing and risk assessment in the Romanian population.*
Position Paper on Treatment of Hepatitis C in Romania 2017. Part Two.
J Gastrointestin Liver Dis
September 2017
Background And Aims: Hepatitis C virus (HCV) infection is a common condition with endemic prevalence in some areas of the world. In Romania, the mean prevalence is about 3%. New treatments have become available on the market in recent years and new drugs are in the pipeline.
View Article and Find Full Text PDFPosition paper on treatment of hepatitis C in Romania, 2017. Part one.
J Gastrointestin Liver Dis
June 2017
Background And Aims: Hepatitis C Virus (HCV) infection is a common condition with endemic prevalence in some areas of the world. In Romania the mean prevalence is about 3%. New treatments became available on the market in recent years and new drugs are in the pipeline.
View Article and Find Full Text PDFColonoscopic detection and removal of polyps represent the most important prevention method for colorectal cancer. We aimed to investigate the diagnostic yield of narrow band imaging (NBI) colonoscopy for polyp detection compared with standard colonoscopy. In this prospective study, 505 patients that underwent total colonoscopy were randomized into two groups: 226 patients in NBI group and 279 in non-NBI group (standard colonoscopy).
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