Publications by authors named "O P Hornstein"

Sweating (perspiratio sensibilis) serves predominantly for thermoregulation and is triggered, among other stimuli, by physical stress. Although consensus on sex-dependent differences in sweating has not been reached so far and recent studies revealing abnormal diminution of the sweating capacity in atopic subjects are mainly based on heat exposure experiments, the influence of endurance training on perspiration in atopics has not yet been evaluated. Using a special sweat collector device reliable even during intensive body movement, we compared the sweat production of age-matched male and female healthy controls (14 m, 10 f) to that of in-patients with atopic eczema (AE: 14 m, 10 f) during and 5 min after physical exercise (30 min) with a bicycle ergometer under standardized experimental conditions.

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Article Synopsis
  • Itching is a unique sensation linked to the body's response to chemical stimuli on skin nerves, which is not fully understood, especially in inflammatory skin diseases like atopic eczema.
  • Recent studies indicate that atopic eczema patients experience reduced itch perception after exposure to substances like histamine and acetylcholine, highlighting different responses in those with or without eczema.
  • The research suggests that while patients with eczema are more likely to feel itch rather than pain from specific irritants, non-atopic individuals show typical pain responses, underscoring different nerve mechanisms at play.
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Background: A characteristic and stable blood flow rhythm can be detected for the skin of the forehead and ear lobes with frequencies of approx. 0.15 Hz (9/min), which were primarily not related to the respiratory rhythm.

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