[Universal Panel of Insertion/Deletion Polymorphisms and Biochip-Based Kit ChipID106 for Genetic Personal Identification].

A panel of 106 insertion/deletion (InDel) polymorphisms and a method of their genotyping on biochips were proposed as a new approach to genetic personal identification. Short lengths and low mutation rates are basic properties of InDel markers, which thus have significant advantages over short tandem repeats (STRs) widely used in forensics. The allele frequency distributions of all known InDel polymorphisms were studied in the five largest world populations (European, East Asian, South Asian, African, and American).

[DNA Phenotyping of Remains from Elite Burials of the Khazar Period of Southern Russia].

Ancient DNA analyses help to solve the problems related to the genogeographic origin and migration patterns of populations. The Khazar Khaganate is a subject of controversy among researchers. Its complex historical development, lack of a sufficient number of artistic and written sources, the disappearance of representatives of Khazar culture leaves open the question of the appearance of the Khazars.

[STRATEGIC DIRECTIONS FOR THE COMPETITIVENESS OF PRIMARY HEALTH CARE ORGANIZATIONS].

The article analyzes the current state of the medical service market of the Russian Federation, including: an assessment of the volume of paid medical services to the population, monetary expenses of households to pay for medical services, expenses of the consolidated budget of the Russian Federation for healthcare, investments in the fixed assets in healthcare, the volume of the pharmaceutical market in Russia and the imports of medicines and medical equipment. The rating of the largest non-governmental medical organizations in Russia in terms of revenue, the number of branches, the cost of initial admission and the number of patients was presented, the total revenue of the top 20 non-governmental medical organizations was analyzed. Negative trends affecting the current state of the medical service market were studied, the risks from the imposition of the sanctions and opportunities for further development of the medical services market were determined; measures of state support for health care in the context of sanctions were discussed.

[A Biochip for Genotyping Polymorphisms Associated with Eye, Hair, Skin Color, AB0 Blood Group, Sex, Y Chromosome Core Haplogroup, and Its Application to Study the Slavic Population].

This paper presents a method for genotyping a panel of 60 single nucleotide polymorphisms (SNPs) using single-stage PCR followed by hybridization on a hydrogel biochip. The pool of analyzed polymorphisms consists of 41 SNPs included in the HIrisPlex-S panel, 4 SNPs of the AB0 gene (261G>Del, 297A>G, 657C>T, 681G>A), markers of the AMELX and AMELY genes, and 14 SNP markers of the Y chromosome haplogroups: B (M60), C (M130), D (CTS3946), E (M5388), G (P257), H (M2920), I (U179), J (M304), L (M185), N (M231), O (M175), Q (M1105), R (P224) and T (M272). These genetic data allow one to predict the phenotype of the desired person according to the characteristics of eye, hair, skin color, AB0 blood group, sex, and genogeographic origin in the male line.

Experimental device for study of the thermal stimulated direct current in the composite materials.

Presents the device for analysis the thermally stimulated electrical conductivity of composites in the wide temperature range. The main advantage of the module in relation to those described earlier is that it allows experiments both in the mode of measuring the current of thermally stimulated depolarization (TSDC) at low temperatures, and in the mode of measuring the thermally stimulated conductivity current (TSCC) up to very high temperatures. Using PMMA/PVDF mixtures as an example, it is shown that the TSDC method can be used to temperature transitions analysis in the many composite materials at low temperatures.