Publications by authors named "O P Astrina"
Aim: To comparatively characterize clinical, biochemical, and hemostasiological parameters in patients with chronic alcoholic hepatitis (CAH) and chronic mixed hepatitis (CMH), i.e. CAH + chronic hepatitis C.
View Article and Find Full Text PDFAim: To ascertain the role of platelets in pathogenesis of clinical symptoms in patients with Q-fever.
Material And Methods: We studied hemostasis with estimation of functional platelet activity in 49 patients with Q-fever.
Results: Hemorrhagic syndrome (HS) occurred in 34.
Aim: to define a role of hemostatic disorders in the pathogenesis of Astrakhan rickettsial fever (ARL).
Subjects And Methods: Platelet functional activity and plasma hemostatic parameters were studied in 89 patients of moderate ARL.
Results: The clinical manifestations of hemostatic disorders at the height of ARL were characterized by the appearance of typhoid maculopapular rashes in 91.
The protective effect of polysaccharide carrageenan on the damaging effect of endotoxins of gram-negative bacteria was studied in vivo and in vitro. Carrageenan increased mouse resistance to the toxic effect of LPS. The degree of protection depended on polysaccharide concentration and administration time and route.
View Article and Find Full Text PDFAim: To study response to laser therapy in different modes and effects on hemocoagulation in patients with acute viral hepatitis B (AVHB).
Material And Methods: Of 173 patients with AVHB, 87 received only basic therapy, 28 patients received placebo (no laser radiation, only signal of the timer) and 58 patients were exposed to laser radiation (32 of them intravenously and 26 supravenously). A course consisted of 10-12 sessions, laser radiation per 1 procedure 300 and 30 mJ, respectively.