Publications by authors named "O Ozden-Akkaya"
Article Synopsis
- The study investigates how bisphenol A (BPA), a common plastic chemical, impacts the formation and health of primordial follicles in the ovary, which are key for female reproduction.
- It highlights the crucial role of the Notch signaling pathway in the communication between oocytes and pregranulosa cells for Folliculogenesis, which BPA might disrupt.
- The research findings reveal that BPA exposure affects the number of ovarian follicles, levels of cell death (apoptosis), and the expression of Notch2 and Jagged2 proteins, with effects varying based on the dosage and timing of exposure.
Article Synopsis
- Bone marrow derived stem cells (BMSC) are the leading choice in bone regeneration, but researchers are exploring other sources like bovine BMSC and adipose tissue derived mesenchymal stem cells (ATSC).
- The study used immunofluorescence and PCR to analyze the osteogenic differentiation of BMSC and ATSC by measuring alkaline phosphatase (ALP) levels and calcium deposition over 21 days.
- Results showed that ATSC exhibited higher ALP levels and calcium deposition initially, indicating faster differentiation, while BMSC ultimately produced more calcium over time, suggesting better long-term mineralization.
Article Synopsis
- Researchers are interested in bovine amniotic fluid-derived mesenchymal stem cells (BAF-MSCs) for stem cell therapy because they are easy to collect and have fewer ethical concerns compared to human cells.
- The study involved isolating and analyzing BAF-MSCs from cattle samples, assessing their properties through various tests to understand their growth patterns and differentiation capabilities.
- Results indicated that BAF-MSCs show potential neurogenic properties, evidenced by changes in specific marker expressions and the ability to form neurospheres, suggesting their future application in clinical settings, although further research is needed to clarify their neurogenic pathways.
Follicular development and other ovarian functions are regulated by growth factors that can be affected by exogenous agents. Methoxychlor (MXC) is an organochloride pesticide that causes female infertility. We investigated how MXC affects the distribution of developing ovarian follicles in adult rats after treatment between embryonic day (E) 18 and postnatal day (PND) 7.
View Article and Find Full Text PDFRenal expression and functions of aquaporin 1 and aquaporin 4 in cattle.
Biotech Histochem
August 2013
Aquaporin (AQP) 1 and AQP 4 are members of the aquaporin water channel family that play an important role in reabsorption of water from the renal tubular fluid to concentrate urine. Studies of renal AQPs have been performed in human, rodents, sheep, dogs and horses. We studied nephron segment-specific expression of AQP 1 and AQP 4 using immunohistochemical staining on paraffin sections of bovine kidneys.
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