The use of combined high-fructose diet and glyphosate to model rats type 2 diabetes symptomatology.

An ideal food-chemical combination that will promote insulin resistance and its consequent development of pancreatic beta-cell dysfunction may open a new vista for Type 2 diabetes (T2D) research. Thus, we investigated the modulatory effects of a high-fructose diet (FRC) combined with glyphosate (GP). Male albino Wistar rats were randomly divided into five groups of eight/group and received distilled water, FRC, GP, and their combinations orally for eight consecutive weeks.

Chemoprotective effects of butanol fraction (Capparidaceae) against type 2 diabetes and oxidative stress in male Wistar rats.

Recent studies have shown that Type 2 diabetes (T2D) in rats can result through a synergy that links obesity to insulin resistance and β-cell dysfunction. The present study achieved T2D via high fructose (20%, p.o.

Aqueous fraction of Alstonia boonei de Wild leaves suppressed inflammatory responses in carrageenan and formaldehyde induced arthritic rats.

Alstonia boonie de Wild is an ethnomedical plant used as therapy against inflammatory disorders. This study evaluated the most active anti-inflammatory and anti-oxidant fraction of A. boonei leaves using in vitro and in vivo models.

Hematological and lipid profile evaluation of a hexane fraction of Costus afer leaves in arthritic rats.

Context: Costus afer Ker Gawl. (Costaceae) is an ethnomedical plant used as therapy against inflammatory disorders.

Objective: The objective of this study was to evaluate the hematological and lipid profile analysis of hexane fraction of C.

Proximate composition, mineral content and in vitro antioxidant activity of leaf and stem of Costus afer (Ginger lily).

Aim: This study was designed to determine the proximate composition and mineral content of Costus afer leaf and stem, as well as to identify the most active antioxidant fraction.

Materials And Methods: The proximate composition and mineral analysis of C. afer leaf and stem were performed using the standard methods described by Pearson and Association of Official Analytical Chemist while the 1,1 diphenyl 2 picryl hydrazyl (DPPH), thiobarbituric acid reactive species (TBARS), lipid peroxidation (LPO), and total antioxidant capacity (TAC) assays were used to determine the in vitro antioxidant activity of aqueous, n-butanol, ethyl acetate and hexane fractions of C.