Influence of Flavonoid-Rich Fraction of Seed Extract on Blood Biochemical Parameters in Streptozotocin-Induced Diabetes Mellitus in Male Wistar Rats.

Diabetes mellitus is a metabolic disorder caused by either the total destruction of the pancreatic beta cells that secrete insulin for the uptake of glucose from the circulation or as a result of the inability of body cells to respond to the presence of insulin in the blood. The present study investigated the effect of a flavonoid-rich fraction of seed extract (FFMTSE) on blood parameters in streptozotocin (STZ)-induced diabetic male Wistar rats. The rats were divided into seven groups ( = 6).

Metabolomics: A Scoping Review of Its Role as a Tool for Disease Biomarker Discovery in Selected Non-Communicable Diseases.

Metabolomics is a branch of 'omics' sciences that utilises a couple of analytical tools for the identification of small molecules (metabolites) in a given sample. The overarching goal of metabolomics is to assess these metabolites quantitatively and qualitatively for their diagnostic, therapeutic, and prognostic potentials. Its use in various aspects of life has been documented.

The chemical composition and membrane stability activity of some herbs used in local therapy for anemia.

The chemical composition and the membrane stabilizing activity of the decoctions of the dry Hibiscus sabdariffa Linn. (Malvaceae) calyx (Sobo in a Nigerian language), Theobroma cacao Linn. (N.

Studies on the acute and sub-chronic toxicity of the essential oil of Ocimum gratissimum L. leaf.

Oral and intra-peritoneal acute toxicity and the sub-chronic intra-peritoneal toxicity of the essential oil of Ocimum gratissimum Linn, Lamiaceae (Ocimum oil), was investigated. The acute toxicity test involved the oral and intra-peritoneal administration of graded doses of Ocimum oil prepared as a 4% v/v emulsion to 2 groups each of 30 rats and mice. LD50 and LD100 were determined for both routes and species.

Effects of isosaline extracts of tetrapleura tetrapetra and olax subscorpioides on certain biochemical parameters of albino rats.

The effects of isosaline extracts of Tetrapleura tetrapetra and Olax subscorpioides were investigated in albino rats. The treatment of rats with these extracts resulted in an increase in the activities of serum alanine aminotransferase, liver aspartate aminotransferase, alanine aminotransferase, acid phosphatase and alkaline phosphatase. The extract of Tetrapleura tetrapetra caused a significant increase in blood glucose and liver glycogen levels while the extract of Olax subscorpioides caused a slight reduction but not statistically significant in the levels of blood glucose and liver glycogen.