Publications by authors named "O O Olutoye"
Introduction: Dysfunction of the enteric nervous system (ENS) is linked to a myriad of gastrointestinal (GI) disorders. Piezo1 is a mechanosensitive ion channel found throughout the GI tract, but its role in the ENS is largely unknown. We hypothesize that Piezo1 plays an important role in the growth and development of the ENS.
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- Congenital diaphragmatic hernia is a serious condition that can lead to issues like underdeveloped lungs and high blood pressure, but a procedure called fetoscopic endoluminal tracheal occlusion (FETO) has shown to improve patient survival despite some complications like tracheomegaly (enlarged trachea).
- A study analyzed 34 patients who underwent FETO, finding that tracheomegaly was present in 24 of them, with most needing intubation right after birth, some requiring a transition to cuffed endotracheal tubes (ETTs) due to concerns like air leaks.
- The findings suggest that larger or cuffed ETTs may be more beneficial for
Introduction: Necrotizing enterocolitis (NEC) is a severe inflammatory disease of the gastrointestinal tract and one of the most common life-threatening emergencies affecting newborns. Intestinal fatty acid-binding protein (I-FABP) has been used as a possible marker of intestinal damage in NEC. We aimed to carry out a scoping review of all publications that explore the role of I-FABP in NEC to inspire new research into the potential utility of I-FABP as a marker of NEC.
View Article and Find Full Text PDFBackground: Necrotizing enterocolitis (NEC) remains a devastating intestinal disease that affects 5-7% of preterm neonates. Remote ischemic conditioning (RIC) has been shown to protect against intestinal ischemia in rodents. We aimed to determine the efficacy of RIC in a large animal model of NEC.
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