Publications by authors named "O O Makinde"

Objectives: The research objectives were to identify and synthesise prevailing definitions and indices of resilience in maternal, newborn, and child health (MNCH) and propose a harmonised definition of resilience in MNCH research and health programmes in low- and middle-income countries (LMICs).

Design: Scoping review using Arksey and O'Malley's framework and a Delphi survey for consensus building.

Participants: Mothers, new-borns, and children living in low- and middle-income countries were selected as participants.

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Article Synopsis
  • This research explores how variable viscosity, activation energy, and microgravity affect the performance of Darcy nanofluid in improving thermal energy storage (TES) via solar collectors.
  • The study emphasizes that using nanofluid can enhance heat and mass transfer in TES applications, which include heat exchangers and solar power systems, especially when combined with solar radiation and phase change materials.
  • A mathematical model is developed to simulate oscillating heat transfer in TES, revealing that lower viscosity increases fluid velocity while higher activation energy and microgravity lead to better thermal and mass transfer efficiencies.
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Faba bean is one of the most important grown plants worldwide for human and animal. Despite its various importance, the productivity of faba bean has been constrained by several biotic and abiotic factors. Many faba bean pathogens have been reported so far, of which the most important yield limiting disease is Chocolate Spot Disease (Botrytis fabae).

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Background: Multidrug-resistant Gram-negative bacterial infections are increasing globally in neonates, infants and children; antibiotic options are limited.

Methods: This international, multicenter, open-label phase 2 study, investigated the pharmacokinetics, safety and tolerability of single-dose and multiple-dose cefiderocol [as a 3-hour infusion (every 8 hours) dosed at 2000 mg for body weight ≥34 kg and at 60 mg/kg for body weight <34 kg], over a range of renal function, in hospitalized pediatric patients with aerobic Gram-negative bacterial infection; multiple-dose patients required standard-of-care systemic antibiotics for 5-14 days. Four cohorts of pediatric patients were enrolled (cohort 1: 12 to <18 years, cohort 2: 6 to <12 years, cohort 3: 2 to <6 years and cohort 4: 3 months to <2 years).

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