Correction for 'Bioactivity of cerium dioxide nanoparticles as a function of size and surface features' by Veronika Sarnatskaya , , 2024, , 2689-2704, https://doi.org/10.1039/D3BM01900D.
View Article and Find Full Text PDFBlending carbon particles (CPs) and nanoscale bioactive cerium dioxide is a promising approach for designing composites for biomedical applications, combining the sorption and antioxidant potentials of each individual component. To address this issue, it is crucial to assess the correlation between the components' ratio, physicochemical parameters, and biofunctionality of the composites. Thus, the current research was aimed at fabricating C@CeO composites with different molar ratios and the examination of how the parameters of the composites affect their bioactivity.
View Article and Find Full Text PDFNano-dispersed cerium dioxide is promising for use in medicine due to its unique physicochemical properties, including low toxicity, the safety of usage, active participation in different redox processes occurring in living cells, and its regenerative potential, manifested in the ability of CeO to participate repeatedly in redox reactions. In this work, we examined the biological activity of cerium dioxide nanoparticles (CeO NPs) synthesized by precipitation in mixed water/alcohol solutions at a constant pH of 9. This synthesis method allowed controlling the size and Ce/Ce proportion on the surface of NPs, changing the synthesis conditions and obtaining highly stable suspensions of "naked" CeO NPs.
View Article and Find Full Text PDFBackground: The development of human breast cancer (BC) is known to be closely related to disturbances in the mammary gland microbiota. Bacteria of the genus Bifidobacterium are an important component of normal breast microbiota and exert antitumor activity. The molecular-biological mechanisms of interaction between BC cells and microbiota members remain poorly studied yet.
View Article and Find Full Text PDFDespite efforts in osteosarcoma (OS) research, the role of inductive moderate hyperthermia (IMH) in delivering and enhancing the antitumor effect of liposomal doxorubicin formulations (LDOX) remains unresolved. This study investigated the effect of a combination treatment with LDOX and IMH on Saos-2 human OS cells. We compared cell viability using a trypan blue assay, apoptosis and reactive oxygen species (ROS) measured by flow cytometry and pro-apoptotic Bax protein expression examined by immunocytochemistry in response to IMH (42 MHz frequency, 15 W power for 30 min), LDOX (0.
View Article and Find Full Text PDF