Late recurrence in patients with non-muscle-invasive bladder cancer after 5-year cancer-free periods.

Objectives: There is no consensus about the follow-up schedule after 5-year cancer-free periods. In this study, we aimed to elucidate the risk factors for the recurrence in patients with non-muscle-invasive bladder cancer who remained cancer free for more than 5 years.

Methods: Data from six Japanese institutions were retrospectively reviewed.

[Clinical study of long graft survival in renal transplantation recipients].

Background: A total of 110 patients, in whom kidneys from 95 living related and 15 cadaver donor, had experienced renal transplantation between February 1985 and October 1996 in our clinic. This study was conducted to evaluate the influence of the various pre-operative factors to the graft survivals and clinical course of patients in living related renal transplantation.

Methods: In 95 recipients, 17 adult patients had long term graft survivals over 5 years including 6 recurrent or denovo nephritis without chronic allografts nephropathy.

[5-Fluorouracil and alpha-2a interferon in patients with hormone-refractory prostate cancer].

Background: Hormone-refractory metastatic prostate cancer remains a disease for were limited therapeutic options are available. Therefore, the establishment of newly, more effective chemotherapy is expected. Experimental data suggest that PC-3, a human hormone refractory prostate cancer cell line, showed a 2-fold increase in 5-Fluorouracil (5FU) sensitivity in the presence of alpha-2a Interferon (IFN alpha 2a) at 100 IU/ml, compared to that without IFN alpha 2a.

Adrenal hemorrhage in the newborn with evidence of bleeding in utero.

A case is reported of adrenal hemorrhage in a newborn with evidence of bleeding while in utero. The patient had a large cystic mass on ultrasound at 36 weeks of gestation. Abdominal computerized tomography after birth also revealed the cystic mass above the left kidney, which became smaller with peripheral calcification when he was 5 months old.