Publications by authors named "O Noel Gill"

Article Synopsis
  • - The Impact Trial evaluated the need and effectiveness of HIV pre-exposure prophylaxis (PrEP) among attendees of sexual health services (SHS) in England from 2017 to 2020, focusing on who could benefit from PrEP and how well it was utilized.
  • - The study included over 21,350 participants, predominantly men who have sex with men (95.5%), with a significant uptake of PrEP at 57.1% among those identified as at risk.
  • - Findings indicated that many participants engaged with the trial by attending follow-up visits, resulting in a median duration of PrEP use of about 361 days, highlighting its role in HIV prevention strategies.
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Background: In the UK, the number of new HIV diagnoses among gay and bisexual men who have sex with men (GBMSM) has decreased substantially. We aimed to understand the contribution of different interventions in reducing HIV incidence so far; to estimate future HIV incidence with continuation of current policies and with further scaling up of current interventions; and to estimate the maximum additional annual cost that should be spent towards these interventions for them to offer value for money.

Methods: We calibrated a dynamic, individual-based, stochastic simulation model, the HIV Synthesis Model, to multiple sources of data on HIV among GBMSM aged 15 years or older in the UK.

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Background: Kidney renal clear cell carcinoma (KIRC) is the most prevalent type of renal cell carcinoma (RCC), with a high incidence and mortality rate. There is a lack of sensitive biomarkers. Therefore, the discovery of accurate biomarkers for KIRC patients is critical to improve prognosis.

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Purpose: International partnerships have an important role in capacity building in global health, but frequently involve travel and its associated carbon footprint. The environmental impact of global health partnerships has not previously been quantified.

Methods: We conducted a retrospective internal audit of the environmental impact of air travel for the international education programs of the Canadian Anesthesiology Society's International Education Fund (CASIEF).

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Background: From 12th March 2020, individuals in England were advised to quarantine in their home if a household member tested positive for SARS-CoV-2. A mandatory isolation period of 10 days was introduced on 28th September 2020 and applied to all individuals with COVID-19. We assessed the frequency, timing, and characteristics of recovered COVID-19 cases requiring subsequent quarantine episodes due to household re-exposure.

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