FEATURES OF BONE REMODELING AROUND SURFACE-MODIFIED TITANIUM AND TANTALUM IMPLANTS.

Objective: The aim: To study the osseointegrative properties of titanium and tantalum implants with different surface structures in animal experiments.

Patients And Methods: Materials and methods: The histological and morphometric study was carried out on 60 male white rats after titanium implants with different surface structures made by 3D printed technology were inserted in the distal femur bone: presented by the multilayered layers of interlacing pores of 300 microns (series 1); rough (> 2 microns) (series 2); and tantalum implants with 300 microns pores and 80% porosity (series 3) as control material.

Results: Results: On the 30 days we found statistically significant differences in the bone-implant contact rate between the 2nd experiment series (44.

MODELS OF PARASPINAL MUSCLE DEGENERATION IN RATS: HIGH-FAT DIET AND PROLONGED COMPRESSION.

Objective: The aim: To study the structural features of the lumbar m. multifidus and the m. psoas after keeping rats on a high-fat diet (obesity) or compressing their lumbar paraspinal muscles by binding the muscles using non-absorbable sutures.

Histological evaluation of the incorporation and remodeling of structural allografts in critical size metaphyseal femur defects in rats of different ages.

Insufficient bone regeneration is a common issue for patients with extensive bone damage, therefore the use of allografts is required. With increasing life expectancy, there is a higher risk of bone repair issues after fractures or orthopedic surgical intervention. We studied incorporation and remodeling of structural allografts in critical size metaphyseal femur defects in 52 rats aged 3-month-old and 12-month-old who underwent surgeries creating a bone defect, which was either filled with a structural allograft (3-month-old - 3moAllo; 12-month-old - 12moAllo) or left empty (3-month-old - 3moE; 12-month-old - 12moE).

REACTIVE-ADJUSTABLE RESTRUCTURING OF STERNUM IN RATS AFTER MODELING OF MECHANICAL LOADING IN THE BIOMECHANICAL SYSTEM "STERNUM-RIBS-SPINE".

Aim of the research - to conduct histological analysis of the sternum immature rats after modeling mechanical loading in the biomechanical system "sternum - ribs - spine". The studies were conducted on 14 rats. In 8 rats a spinal deformity was simulated according to the method of Sarwark JF et al.

BONE REPAIR AFTER THE GLASS-CERAMICS IMPLANTATION INTO THE RATS' FEMUR DEFECT.

The aim is to study the bone response to the implantation of two glass-ceramic materials into the distal metaphysis of the femur of rats. Experiment was carried out on 30 white 4-month-old laboratory male rats. Animals were randomly divided into two groups for the implantation of two types of calcium silicate-phosphate glasses (BS-11 or ASZ-5) into the defect of femur.