Publications by authors named "O N Zhuravleva"
Objective: Atrial cardiomyopathy is closely associated with atrial fibrillation (AF), and some patients exhibit no dysfunction at rest but demonstrate evident changes in left atrial (LA) function and LA volume during exercise. This study aimed to identify distinguishing signs during exercise stress echocardiography (ESE) among patients in sinus rhythm (SR), with and without history of paroxysmal/persistent AF (PAF).
Methods: A prospective cohort of 1055 patients in SR was enrolled across 12 centers.
Aim: To assess the role of clinical indicators and parameters of stress echocardiography performed according to an extended protocol as predictors for the occurrence of a composite cardiovascular endpoint (CCVEP) in IHD.
Material And Methods: The study included 186 patients (60.2% men, mean age 60.
Article Synopsis
- The high death rate from acute myocardial infarction (AMI) highlights the urgent need for more effective treatments in modern cardiology, particularly through new drug development.
- Enzyme-resistant peptide analogs of glucagon-like peptide-1 (GLP-1) could serve as promising therapies, as GLP-1 receptor (GLP1R) agonists show potential in preventing cardiac injury and adverse remodeling following heart-related issues.
- These GLP1R agonists work by protecting heart cells from stress, reducing inflammation, and promoting cell survival through various cellular pathways, thereby improving heart health in conditions like myocardial infarction, hypertension, and diabetes.
Two new cyclopiane diterpenes and a new cladosporin precursor, together with four known related compounds, were isolated from the marine sediment-derived fungus KMM 4670, which was re-identified based on phylogenetic inference from ITS, , , and gene regions. The absolute stereostructures of the isolated cyclopianes were determined using modified Mosher's method and quantum chemical calculations of the ECD spectra. The isolation from the natural source of two biosynthetic precursors of cladosporin from a natural source has been reported for the first time.
View Article and Find Full Text PDFNew anthraquinone derivatives acruciquinones A-C (-), together with ten known metabolites, were isolated from the obligate marine fungus KMM 4696. Acruciquinone C is the first member of anthraquinone derivatives with a 6/6/5 backbone. The structures of isolated compounds were established based on NMR and MS data.
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