Publications by authors named "O N Uchakina"
The lack of routine viral genomic surveillance delayed the initial detection of SARS-CoV-2, allowing the virus to spread unfettered at the outset of the U.S. epidemic.
View Article and Find Full Text PDFUnlabelled: The lack of routine viral genomic surveillance delayed the initial detection of SARS-CoV-2, allowing the virus to spread unfettered at the outset of the U.S. epidemic.
View Article and Find Full Text PDFMercury is a heavy metal toxicant that is prevalent throughout the environment. Organic forms of mercury, such as methylmercury (MeHg), can cross the placenta and can lead to lasting detrimental effects in the fetus. The toxicological effects of MeHg on the placenta itself have not been clearly defined.
View Article and Find Full Text PDFBackground: Immunomodulatory effects of macrolides in chronic inflammation are well known. In this study, we tested our hypothesis that azithromycin (AZT) can decrease inflammation in pediatric patients with sickle cell disease (SCD).
Methods: The use of AZT as an anti-inflammatory agent was evaluated in double-blind, placebo-controlled, cross-over study for 8 weeks of treatment with 8 weeks of washout.
Article Synopsis
- Elemental mercury (Hg) contamination is common in artisanal and small-scale gold mining communities, where contaminated tailings are reprocessed using cyanide (CN) to extract leftover gold.
- Hg reacts with CN to form stable complexes like Hg(CN), which become more soluble and dispersed in agitated conditions, potentially increasing their toxicity.
- Research on adult rats shows that Hg(CN) accumulates mainly in the kidneys, with possible damage at low concentrations, but little accumulation occurs in the brain, indicating these complexes might not pass the blood-brain barrier.