Effects of ciprofloxacin, streptomycin, and gentamicin on rabbit corneal transendothelial electrical potential difference.

Purpose: A previous report suggested that high concentrations of ciprofloxacin in the anterior chamber may cause dose-dependent acute corneal decompensation. Therefore we evaluated the effect of varying concentrations of ciprofloxacin in the anterior chamber on the corneal endothelium and compared these effects with those of gentamicin and streptomycin.

Methods: We assessed endothelial transport function by determining transendothelial electrical potential differences (TEPDs) of rabbit corneas.

Penetrating keratoplasty for keratoconus: role of videokeratoscopy and trephine sizing.

Purpose: To evaluate whether determining graft-host trephine disparity on the basis of videokeratoscopic data of keratoconus patients having penetrating keratoplasty (PKP) reduces ametropia and to correlate preoperative videokeratoscopic values, posterior axial length (PAL), and trephine disparity with postoperative refractive outcomes.

Setting: Hôtel-Dieu, University of Paris, France.

Methods: This randomized clinical trial comprised 18 keratoconus patients who had PKP.

Videokeratoscopy of recipient peripheral corneas in combined penetrating keratoplasty, cataract extraction, and lens implantation.

Purpose: We performed a prospective clinical trial to evaluate computerized videokeratoscopic analysis of the peripheral recipient cornea in intraocular lens power calculations for triple procedures: penetrating keratoplasty, cataract extraction, and intraocular lens insertion.

Methods: Patients with Fuchs' dystrophy underwent consecutive triple procedures. Surgery was performed in 16 eyes by a single surgeon (O.