Tissue hypoxia and intestinal dysbiosis in children with tuberculosis.

We studied the role of autochthonous microflora from body cavities in the development of tissue hypoxia and instability of cell membranes. In children with tuberculosis dysbiosis manifested in nonspecific quantitative changes in the intestinal microflora and the presence of coxsackievirus antigens in the urine. DNA-containing viruses with pronounced immunosuppressive activity (e.

[Tuberculous meningitis in infants].

Tuberculous meningitis (TM) develops more frequently in unvaccinated or inadequately vaccinated infants (28 cases of 34), in contact infants (26 of 34 cases). Within the first year of life TM is especially aggressive. Late diagnosis and treatment leave significant residual neurological changes or result in lethal outcomes.