Efficacy of Combination Neoadjuvant Chemotherapy and Regional Inductive Moderate Hyperthermia in the Treatment of Patients With Locally Advanced Breast Cancer.

Purpose: To evaluate the efficacy of neoadjuvant chemotherapy in combination with regional inductive moderate hyperthermia for patients with locally advanced breast cancer.

Patients And Methods: 200 patients with stage IIB-IIIA breast cancer received neoadjuvant chemotherapy (control group, n = 97) or chemotherapy combined with hyperthermia (experimental group, n = 103). Inductive hyperthermia was set at 27.

[Photometric determination of copper in the blood].

Copper complex formation and extraction with rhodanide ions and a cyanin stain, cation violet, were studied. The reaction is characterized by a high sensitivity and specificity. A new method for blood copper extraction photometry has been developed.

[The characteristics of using mineral waters with an increased boron content in rehabilitating patients with hepatobiliary pathology].

Changes in biochemical bile composition were investigated in 42 patients with chronic infective acalculous cholecystitis on combined sanatorium treatment. In those with carbohydrate dysbolism, bile production was found inhibited possibly due to the intake of carbonate sodium mineral water of moderate mineralization containing bromine and fluorine with high concentrations of bromine, in particular.

[Criteria for the evaluation of the biochemical composition of bile].

The authors suggest additional criteria evidencing inflammations in the gallbladder and colloid stability of the bile: bile acid absorption and cholesterol sedimentation coefficients. Derivation of these coefficients is based on biochemical examination of the bile with measurements of bile acid, cholesterol, and bilirubin concentrations in both portions. The results of examinations of 99 subjects evidence the diagnostic value and specificity of the characteristics, and availability of this method for clinical practice.

[The effect of chronic internal irradiation from incorporated radionuclides on liver function].

On chronic supply to the body of a mixture of nuclear division products lanthanum-140, barium-140, tellurium-132, neodymium-147, neptunium-239, zirconium-95, niobium-95, iodine-131, cerium-141, -144, cesium-134, -137, and ruthenium-103 are detectable in liver tissue within the first months. In the 2 to 4 years following the disaster, liver tissue primarily accumulates cerium-144, radium-226, thorium-228, -232, ruthenium-106, antimony-125, and europium-154. Within the first periods the liver radionuclide content was 19 to 31% higher than that in the blood, and in the following years it was 24 to 38% higher.