Mice display learning and behavioral deficits after a 30-day spaceflight on Bion-M1 satellite.

Profound effects of spaceflight on the physiology of humans and non-human animals are well-documented but incompletely explored. Current goals to undertake interplanetary missions increase the urgency to learn more about adaptation to prolonged spaceflight and readaptation to Earth-normal conditions, especially with the inclusion of radiation exposures greater than those confronted in traditional, orbital flights. The 30-day-long Bion M-1 biosatellite flight was conducted at a relatively high orbit, exposing the mice to greater doses of radiation in addition to microgravity, a combination of factors relevant to Mars missions.

[Rhinosinusitis in Hurler syndrome patients requiring hematopoietic stem cells transplantation].

Introduction: Allogenic transplantation of hemopoetic stem cells (allo-THSC) is one of the most effective treatment methods for Hurler syndrome, aimed at maximal correction of complications related to the genetic disorder. Presence of infection in the recipient is an adverse risk factor, affecting the possibility of starting the conditioning regimen and THSC peforming in general.

Aim: To assess the condition of the nasal cavity and paranasal sinuses in Hurler syndrome patients before the allo-THSC, dynamics of these changes after the transplantation taking into account the correction of alpha-L-iduronidase enzyme level with donor blood cells.

Probing pairing symmetry in multi-band superconductors by quasiparticle interference.

We study momentum and energy dependencies of the quasiparticle interference (QPI) response function in multiband superconductors in the framework of the strong-coupling Eliashberg approach. Within an effective two-band model we study the s and s symmetry cases, corresponding to opposite or equal signs of the order parameters in the bands. We demonstrate that the momentum dependence of the QPI function is strikingly different for s and s symmetries of the order parameter at energies close to the small gap.

Adaptation to a blood pressure telemetry system revealed by measures of activity, agility and operant learning in mice.

Introduction: Implantable telemetry enables continuous monitoring of physiological functions in freely moving animals and can greatly complement pharmacological research. Despite its miniaturization, a sensor/transmitter constitutes 5% or more of a mouse's bodyweight. The aim of the present study was to evaluate whether factors related to the presence of a probe/transmitter influence the ambulatory activity, strength, agility, or operant, motivated behaviors of this small rodent.

[Determination of the rational extent of laser-assisted resection for the treatment of paralytic laryngeal stenosis].

The objective of the present study was to improve the procedures for extended and restricted laser-assisted laryngoplasty in the patients presenting withparalytic laryngeal stenosis and to evaluate the outcome of the surgical interventionsdiffering in extent. The study included 51 patients (47 women and 4 men) at the age varying from 18 to 78 years. Twenty five of these patients had a tracheostoma.