Publications by authors named "O N Cherkasova"
Article Synopsis
- The study aimed to assess dental health and systemic immunity in 74 patients aged 8-18 with congenital cleft lip and palate, comparing those with unilateral and bilateral conditions.
- Results showed high caries rates in patients, especially those with bilateral cleft lip and palate, where nearly 42% had severe dental issues, and chronic gingivitis was prevalent in both groups.
- The research concluded that significant dental and immune system changes are observed in these patients, with the severity of issues increasing with the extent of the cleft condition.
In vivo MRS study of long-term effects of traumatic intracranial injection of a culture medium in mice.
Vavilovskii Zhurnal Genet Selektsii
October 2023
Orthotopic transplantation of glioblastoma cells in the brain of laboratory mice is a common animal model for studying brain tumors. It was shown that 1H magnetic resonance spectroscopy (MRS) enables monitoring of the tumor's occurrence and its development during therapy based on the ratio of several metabolites. However, in studying new approaches to the therapy of glioblastoma in the model of orthotopic xenotransplantation of glioma cells into the brain of mice, it is necessary to understand which metabolites are produced by a growing tumor and which are the result of tumor cells injection along the modeling of the pathology.
View Article and Find Full Text PDFObjective: The aim: To determine the dental status and state of local immunity in young adults who have suffered from the coronavirus disease.
Patients And Methods: Materials and methods: The main group consisted of 30 people aged 20-22 years, who suffered from the coronavirus infection Covid19 6.1±1.
Objective: The aim: To establish the clinical and immunological features of the course of caries in young people who have suffered from the coronavirus disease.
Patients And Methods: Materials and methods: The main group consisted of 30 people aged 20,6±2,4 years who suffered from the Covid19 coronavirus infection 6,1±1,2 months ago. All patients underwent a dental and immunological examination.
The most commonly occurring malignant brain tumors are gliomas, and among them is glioblastoma multiforme. The main idea of the paper is to estimate dependency between glioma tissue and blood serum biomarkers using Raman spectroscopy. We used the most common model of human glioma when continuous cell lines, such as U87, derived from primary human tumor cells, are transplanted intracranially into the mouse brain.
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