[New Targets in Blood Pressure Control: Arguments Pro and Contra].

The review contains results of analysis of clinical studies on the problem of defining the target level of the blood pressure (BP). The rationale for selection the target systolic BP level below120 mmHg was obtained in the SPRINT study comparing the target levels <120 mmHg and <140 mmHg. A considerably lower number of cardiovascular complications and deaths was seen in the group of a stricter BP control.

[Interdisciplinary approach to evaluation of metabolic syndrome in locomotive crew workers].

The authors revealed features of metabolic syndrome diagnosis by means of various intradisciplinary criteria in locomotive crew workers. The locomotive crew workers, if compared to mounters, demonstrate 1.4 times more frequent excessive body weight, 1.

[Effect of psychosocial stress on the level of anxiety, depression and behavioral risk factors of cardiovascular diseases in men].

Aim: To elucidate peculiarities of risk factors (RF) of cardiovascular diseases and frequency of arterial hypertension (AH) at place of work in men with various level of psychosocial stress.

Material And Methods: We examined 224 men (and their assistants) aged 22-55 years. Examination included analysis of risk factors, assessment of psychoemotional status (self-assessment of psychosocial stress using Reeder Stress Inventory [RSI] and Hospital Anxiety and Depression Scale [HADS]), detection of AH at working place by "Mathematical calculation" stress test.

Effects of liraglutide on neurodegeneration, blood flow and cognition in Alzheimer´s disease - protocol for a controlled, randomized double-blinded trial.

Introduction: Type 2 diabetes (DM-2) increases the risk of developing Alzheimer´s disease (AD), and patients with AD are more likely to develop DM-2. DM-2 and AD share some pathophysiological features. In AD, amyloid-β (Aβ) is accumulated as extracellular plaques in the gray matter of the brain, while in DM-2 islet amyloid polypeptide (IAPP) is accumulated in the pancreas.

[Professional stress and development of stress-induced hypertension].

to elucidate rates of development of arterial hypertension (AH) at working place (wp), risk factors of cardiovascular diseases (CVD), anxiety depressive disorders in persons with professional stress. We carried out monitoring of arterial pressure during working hours and hours of rest, assessed risk factors of CVD development, and evaluated severity of symptoms of anxiety and depression using the Hamilton scale in 138 men (mean age 40.0+/-1.