Publications by authors named "O Maly"

Intensive fish farming is associated with a high level of stress, causing immunosuppression. Immunomodulators of natural origin, such as probiotics or phytoadditives, represent a promising alternative for increasing the immune function of fish. In this study, we tested the autochthonous trout probiotic strain R2 in a newly developed, low-cost application form ensuring the rapid revitalization of bacteria.

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Disease conditions that involve multiple predisposing or contributing factors, or manifest as low performance and/or low-level mortality, can pose a diagnostic challenge that requires an interdisciplinary approach. Reaching a diagnosis may also be limited by a lack of available clinical profile parameter reference ranges to discriminate healthy fish from those affected by specific disease conditions. Here, we describe our experience investigating poorly performing rainbow trout () in an intensive recirculation aquaculture, where reaching a final diagnosis of nephrocalcinosis was not as straightforward as one would wish.

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The distribution of mercury species was studied in all aquatic ecosystem components (i.e., water, sediment, emergent aquatic plants, invertebrates and omnivorous and piscivorous fish) of the Záskalská water reservoir (Central Bohemia, Czech Republic) which is in the vicinity of an abandoned cinnabar mine.

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Article Synopsis
  • The study investigated how different doses of fluoxetine in food affect juvenile rainbow trout, focusing on their morphology, hematology, biochemistry, and oxidative stress.* -
  • Significant changes were observed in the fish's immune response, with an increased neutrophil/lymphocyte ratio and decreased lymphocyte count, alongside reduced detoxifying enzyme activity in the liver and kidney.* -
  • Histopathological analysis showed damage to the kidney's proximal tubules, confirming that fluoxetine has notable adverse effects on the health of rainbow trout.*
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Article Synopsis
  • The study investigates the role of antioxidant enzyme gene expression in Crohn's disease (CD) by analyzing surgically removed intestinal tissues from 28 patients, focusing on both inflamed and normal areas.* -
  • Results showed significantly lower levels of SOD1 and GSR mRNA in inflamed tissues, suggesting a potential link between reduced antioxidant defenses and tissue damage in CD, while no significant differences were observed for other enzymes like SOD2 and GPX.* -
  • The findings indicate that antioxidant gene expression varies in CD, with decreased SOD1 and GSR possibly contributing to localized tissue injury from reactive oxygen species.*
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