[The possibilities of congenital pathology primary prophylaxis as responsibility of general practitioner in Ukraine].

Unlabelled: The aim was to study some tendencies of congenital pathology primary prophylaxis in context of Governmental measures and general practitioner's activity.

Materials And Methods: The information basis of investigation was made up from foreign and home publications, lawmaking documents and data of questioners. Questioners were filled in by doctors who obtained general practitioner qualification (152 persons).

[Normative-legal support for implementation of national strategy of glaucoma control in Ukraine].

The review of normative legal database for implementation of national strategy of glaucoma control has demonstrated that there are all terms and conditions for implementation of national strategy on the national level. There is no necessity to change present normative legal database in the field of public health for the purpose of strategy implementation.

[Effect of succinylation of Klebsiella 45 bacteriophage proteins on specific lytic activity].

Effect of different levels of virions protein acylation on lytic activity, parameters of interaction with sensitive bacterial cells and other biological properties of phages has been studied in experiments on Klebsiella 45 bacteriophage. It was shown that at 5-, 10- and 20% levels of the phage sample acylation the specific lytic activity increased 90, 12 and 8 times, respectively, adsorbtion velocity constant increased 9, 8 and 8 times, respectively, and latent period decreases by 20% in all cases of the development of productive infection caused by succinylated phages. Such chemical modification did not change morphology, antigenic structure of phase virions, did not take essential effect on the spectrum of lytic activity and average yield of infectious phage corpuscles per a sensitive bacterial cell.

[Chemically modified specific immunoglobulins for legionellosis laboratory diagnostics].

On an example of the rabbit antilegionella immunoglobulins (antLegIgRb) and monospecific human serum (antLegSerHum) the influence of a protein with different acylation level on specific and nonspecific activity of the above immunobiopreparations was investigated. It was determined, that 5 % level of chemical modification provides the highest level of augmentation (2.0-2.

[The physiological characteristics of the antioxidant properties of Lipin in bronchial asthma in children].

In children of 4-7 years old with bronchial asthma (BA) has been studied the values of lipid peroxidation, antioxidant status and some others in blood plasma and erythrocytes without and with the use of new drug Lipin. It was shown that in children with BA the malondialdehyde concentration increased, the superoxydedismutase activity decreased, the NAD concentration increased, and the ratio of superoxidedismutase/malondialdehyde greatly decreased in comparison with normal children. The use of Lipin led to diminuation of lipid peroxidation, to marked increase of superoxidedismutase activity, to decrease of NAD concentration, and to significant increase of superoxidedismutase/malondialdehyde ratio.