Publications by authors named "O M Rozanova"

Article Synopsis
  • This study aimed to determine the relative biological effectiveness (RBE) of carbon ion beams in particle radiotherapy, focusing on different regions of the Bragg curve while comparing it to X-ray radiation.
  • SHK mice were irradiated at varying doses (0-1.5 Gy for cytogenetic damage and 6.5 Gy for survival) to assess the effects of carbon ions in the Bragg peak using different widths of the spread-out Bragg peak (SOBP).
  • Results indicated that RBE values were lower before and after the Bragg peak (0.8-0.9), but increased significantly in the low-dose region (1.1-1.7 for 10-mm SOBP), suggesting
View Article and Find Full Text PDF

Direct trophic links between aboveground and belowground animal communities are rarely considered in food web models. Most invertebrate animals inhabiting aboveground space eventually become prey of soil predators and scavengers forming a gravity-driven spatial subsidy to detrital food webs, but its importance remains unquantified. We used laboratory-grown N-labeled Collembola to trace the incorporation of arthropod rain into soil food webs.

View Article and Find Full Text PDF

Radiosensitivity to low and medium doses of X-ray radiation and the ability to induce a radiation adaptive response (RAR) of lymphocytes during in vitro irradiation of peripheral blood of patients with cancer were studied. The criterion for cytogenetic damage was the frequency of micronuclei (MN) in cytochalasin-blocked binucleate lymphocytes in culture. It was found that the spontaneous level of cytogenetic damage in the lymphocytes of patients was 2.

View Article and Find Full Text PDF

The effect of carbon ions (C) with the energy of 400 MeV/nucleon on the dynamics of induction and growth rate of solid tumors in mice under irradiation of Ehrlich ascites carcinoma cells (EAC) ex vivo at doses of 5-30 Gy relative to the action of equally effective doses of X-ray radiation was studied. The dynamics of tumor induction under the action of C and X-rays had a similar character and depended on the dose during 3 months of observation. The value of the latent period, both when irradiating cells with C and X-ray, increased with increasing dose, and the interval for tumor induction decreased.

View Article and Find Full Text PDF

This study presents data on the growth rate and frequency of induction of the solid form of Ehrlich's ascites carcinoma (EAC) in mice in the short and long term after inoculation of ascitic cells irradiated ex vivo with a proton beam in the dose range of 30-150 Gy. It was shown that the growth rate of solid tumors after inoculation of irradiated cells ex vivo coincided with the growth of tumors in the control group. The frequency of tumor induction in mice after inoculation of EAC cells irradiated at a dose of 30 Gy was 80%, 60 Gy-60%, 90 Gy-25%, and 120 Gy-10%; at irradiation at a dose of 150 Gy, no tumors appeared during the entire observation period.

View Article and Find Full Text PDF