Potential therapeutic applications of mesenchymal stem cells in the oral and maxillofacial tissues.

Over the past decades, we have noted that the study of stem cells is of interest to scientists because it offers great promise for the development of cell-based therapies and establishes basic models for studying the pathogenesis of diseases, overcoming all the challenges it encounters. The majority of craniofacial tissues are derived from mesenchymal tissues, so it makes the mesenchymal stem cells (MSCs) an attractive candidate for regenerating damaged or diseased craniofacial structures. Mesenchymal stem cells (MSCs) do not have the same obstacles as embryonic stem cells.

Limited Evidence Suggests Guided Bone Regeneration With or Without Autogenous Bone Grafts are Equivalently Effective in Horizontal Bone Gain.

Article Title And Bibliographic Information: Horizontal ridge augmentation with guided bone regeneration using particulate xenogenic bone substitutes with or without autogenous block grafts: A randomized controlled trial. Mendoza-Azpur G, de la Fuente A, Chavez E, Valdivia E, Khouly I. Clin Implant Dent Relat Res 2019;1-10.

The Effect of Using Bone Marrow Mesenchymal Stem Cells Versus Platelet Rich Plasma on the Healing of Induced Oral Ulcer in Albino Rats.

Background And Objectives: Oral ulceration is one of the most common debilitating condition that affects the oral cavity. In this study, the effect of locally injected platelet rich plasma (PRP) and bone marrow-derived mesenchymal stem cells (BMSCs) on the healing of oral ulcer was investigated.

Methods And Results: An ulcer was induced in buccal mucosa of rats by using 5mm biopsy punch followed by application of cotton swab soaked with formocresol for 60sec.