Publications by authors named "O M Altamimi"
Monoamine oxidase B (MAO-B) is a key enzyme in the mitochondrial outer membrane, pivotal for the oxidative deamination of biogenic amines. Its overexpression has been implicated in the pathogenesis of several cancers, including glioblastoma and colorectal, lung, renal, and bladder cancers, primarily through the increased production of reactive oxygen species (ROS). Inhibition of MAO-B impedes cell proliferation, making it a potential therapeutic target.
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- The study focuses on Nabatean savory, a plant native to Saudi Arabia, analyzing its leaves and stems for phytochemical content and biological properties.
- The extracts were tested for antioxidant, antimicrobial, and anticancer effects, revealing that the stem extract had stronger activity than the leaf extract, especially against human malignant cell lines.
- Molecular analysis identified key chemical constituents and showed that stem extract could potentially serve as an alternative to chemotherapy due to its significant health benefits.
Shwan sub-Basin is one of the substantial groundwater sources in northern Iraq. Along with an increase in population, agricultural and industrial activities synced with the change in climate conditions, all could have a negative impact on the hydrochemistry of groundwater. Therefore, it becomes crucial to investigate the different processes that could affect hydrochemistry and water quality.
View Article and Find Full Text PDFBackground: Knee joint osteoarthritis is the most common among older adults. The knee joint needs to be treated surgically. The prevalence of this disorder is believed to be higher than 40% among people over 60.
View Article and Find Full Text PDFBackground: The novel severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) outbreak has affected ST-elevation myocardial infarction (STEMI) care worldwide. Reports from China, Europa, and North America showed a significant decline in STEMI volume with a simultaneous increase in time from symptoms to hospital presentation.
Aim: The aim of the study was to study the effect of the SARS-CoV-2 outbreak on primary percutaneous coronary intervention (PPCI) volume performed for STEMI, symptom onset to hospital presentation time (symptom-to-door [S2D]), and door-to-balloon time (D2B) at the main nationwide PPCI center in Qatar.