[Biological characteristics of microorganisms for prognosis of trophic ulcers course].

Aim: To substantiate the possibility to use the biological characteristics of microorganism, in particular, factors of its persistence, for assessment of severity of trophic ulcers of lower extremities.

Materials And Methods: Clinical examinations and bacteriological tests of 48 patients aged from 37 to 80 years with trophic ulcer of lower limbs were performed. Antilysozyme, anticomplement, anticarnosine as well as hemolytic activity of isolated microorganisms were assessed.

[Prediction of the course of acute purulent diseases of the lung and pleura].

The paper presents the data of examination of 62 patients with acute purulent diseases of the lung and pleura (abscess, empyema, pyopneumothorax). The persistent and virulent characteristics of causative agents isolated just from a suppuration focus during its puncture are described. There was an association of the high level of antilysozyme, anticomplementary, and hemolytic activities of bacterial pathogens with the severe course of a disease.

[Treatment of acute pyoinflammatory diseases of the lungs and pleura under control of microorganism persistence factors].

Results of treatment of patients with acute pulmonary abscess, acute empyema of the pleura and pyopneumothorax were analyzed. The local treatment of the main group of patients consisting of 50 persons included oxitocin in combination with antiseptics and antibiotics which facilitated maximal reduction of the persistent potential of the pathogenic agent, its rapid elimination from the purulent focus and allowed to get better results using conservative therapy. The obtained clinical effect confirmed the experimental data on pronounced inhibition of persistent properties of the bacterial pathogens with the complexes "antibiotic-oxitocin".

[Biological properties of microorganisms as the basis for the prognosis of the severity of pyoinflammatory pleuropulmonary diseases].

In the study of 65 microbial cultures isolated from the purulent foci in acute pulmonary abscess and acute pyothorax of 48 patients, a wide spectrum of microflora was detected. Staphylococci and Pseudomonas prevailed among aerobes, bacteroids and peptostreptococci--among anaerobes. In cases of the prolonged course of the pathological process, as compared with the common one, microorganisms exhibited hemolytic activity and high antilysozyme and anticomplementary levels.