Publications by authors named "O M Abdel Latif"

Background: Chronic spontaneous urticaria (CSU) is a persistent skin condition with no known cause or trigger. The unpredictability of CSU attacks lowers patients' quality of life. NOD-like receptor pyrin domain containing 3 (NLRP3) gene dysregulation can result in numerous immunological and inflammatory diseases.

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  • Chronic spontaneous urticaria (CSU) is a complex condition, and this study explored the connection between serum zonulin levels, a marker for "leaky gut," and CSU among patients.
  • The study included 97 CSU patients and 87 healthy controls, revealing that CSU patients had significantly lower zonulin levels than the controls (median of 2.93 ng/ml versus 3.92 ng/ml).
  • Although a positive correlation was found between serum zonulin and C-reactive protein, no significant relationship was established between zonulin levels and disease activity or immunoglobulin E levels, suggesting factors like diet and medication could impact zonulin levels in CSU patients.
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  • Migration of a fragmented sternal wire is a rare complication after cardiovascular surgery, with clinical symptoms ranging from being asymptomatic to severe hemodynamic instability.* -
  • A retrospective review revealed 13 cases of this issue, primarily affecting older men (median age 64), with nearly half experiencing hemorrhagic shock, and most cases presenting either shortly after surgery or years later.* -
  • Identifying this complication often involves CT scans, but successful management requires careful attention to the patient's specific situation following diagnosis.*
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  • An AI-based ECG model is effective in identifying patients at risk for low ejection fraction (EF), particularly noting that those with abnormal AI-ECG scores and normal EF (false positives or FPs) were more likely to develop low EF later on.
  • This study analyzed echocardiographic features and all-cause mortality risk in a large cohort of patients, categorizing them into groups like true negatives (TN), false positives (FP), true positives (TP), and false negatives (FN), using these categorization techniques to assess heart health.
  • Results showed that 97% of FPs had some echocardiographic abnormality; they faced a significantly higher risk of mortality compared to
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  • Secondary mitral regurgitation (MR) worsens in 10-15% of heart failure patients receiving cardiac resynchronization therapy (CRT), and transcatheter edge-to-edge repair (TEER) with Mitra-Clip shows promise in improving outcomes for those who are CRT non-responders.
  • A meta-analysis of 439 patients indicated that Mitra-Clip significantly reduced MR severity and improved symptoms in a majority of CRT non-responders within six months and one year post-procedure.
  • The mortality rates for patients after undergoing TEER with Mitra-Clip were similar to those observed in previous studies, with 30-day, 6-month, 1-year, and 2-year mortality rates at
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